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Biophysical Sciences Institute

Technologies and Methodologies

The development of technologies, methodologies and their applications in biology is a dynamic area of research in the BSI.  For more information about any of the individual technologies and methodologies and how they are being applied within the BSI please follow these links:


Biomembrane models and cells at an interface between two aqueous phases, each phase mimicking either extra or intra cellular fluids, are studied for characterising the interactions of molecules with bilayer lipid membranes (BLMs) and for assembling 'soft' implantable sensing materials.


Electrochemical sensors, both disposable and on-line, are developed and characterised for application in 'harsh' samples such as plasma, whole blood and brackish media.


Supported by both the BHF and EPSRC, a high resolution SPIM (Single Plain Illumination Microscopy) is being developed to record high-resolution 3D images of a beating heart within zebra fish. 


Advanced protein characterisation, protein folding and post-translational modification largely supported by BBSRC.


This work aims to provide a key bioimage informatics technology for significant deepening and broadening of our knowledge and understanding of biological systems, which will open novel avenues for life sciences and beyond.


Contact Details

Biophysical Sciences Institute
Durham University.
South Road,
Durham,
DH1 3LE
+44 (0) 191 334 2351

email: admin.bsi@durham.ac.uk