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Durham University

Department of Biosciences

Profile

Publication details for Professor Paul Denny

Eggimann, G.A., Bolt, H.L., Denny, P.W. & Cobb, S.L. (2015). Investigating the Anti-leishmanial Effects of Linear Peptoids. ChemMedChem 10(3): 233-237.

Author(s) from Durham

Abstract

Peptoids, a class of peptide mimetics, have emerged as promising anti-infective agents against a range of bacterial infections. Herein we present the first study of the antiparasitic and specifically the anti-leishmanial properties of linear peptoids. Peptoids were identified as having promising activity against Leishmania mexicana axenic amastigotes, a causative agent of cutaneous leishmaniasis.