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Durham University

Department of Biosciences


Publication details for Prof PJ Hussey

Zang, J., Zhang, T., Hussey, P.J. & Wang, P. (2020). Light microscopy of the endoplasmic reticulum‐membrane contact sites in plants. Journal of Microscopy 280(2): 134-139.

Author(s) from Durham


The existence of membrane contact sites (MCS) has been reported in different systems in the past decade, and their importance has been recognized by the cell biology community. Amongst all endomembrane structures, the endoplasmic reticulum (ER) plays vital roles in organizing the organelle interaction network with the plasma membrane (PM), Golgi bodies, mitochondria, plastids, endosomes and autophagosomes. A number of methods have been used to study the establishment and functions of these interactions, among them, light microscopy appears to be one of the most effective approaches. Here, we present an overview of the discovery of ER‐PM contact sites, and highlight the latest developments in light microscopical‐based techniques that can be used for their study.