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Research

Research lectures, seminars and events

The events listed in this area are research seminars, workshops and lectures hosted by Durham University departments and research institutes. If you are not a member of the University, but  wish to enquire about attending one of the events please contact the organiser or host department.


 

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Events for 13 November 2017

Graeme Hickey: Joint modelling of multivariate longitudinal and time-to-event data

12:00am, CM221

Research into joint modelling methods of a longitudinal and time-to-event outcome has grown substantially over recent years. Previous research has predominantly concentrated on joint models involving a single longitudinal outcome. In clinical practice, the data collected will be more complex, featuring multiple longitudinal outcomes and/or multiple, recurrent or competing event times. Harnessing all available measurements in a single model is advantageous and should lead to improved and more specific model predictions.

Notwithstanding the increased flexibility and better predictive capabilities, the extension of the classical univariate joint modelling framework to a multivariate setting introduces a number of technical and computational challenges. These include the high-dimensional numerical integrations required, modelling of multivariate unbalanced data, and proper estimation of standard errors. Consequently, software capable of fitting joint models to multivariate data is lacking. Building on recent methodological developments, we extend the classical joint model to multiple continuous longitudinal outcomes, and describe how to fit it using a Monte Carlo Expectation-Maximization algorithm with antithetic simulation for variance reduction. The development of a new R package will be discussed. An application to a recent clinical trial dataset will be presented.

Contact sunil.chhita@durham.ac.uk for more information about this event.


IAS Fellow's Seminar - Politics, psychotherapy and the puzzle of dualism

1:00pm to 2:00pm, IAS Seminar Room, Palace Green, Dr Wahbie Long (University of Cape Town)

Contact enquiries.ias@durham.ac.uk for more information about this event.


Tom Fisher: The proportion of plane cubic curves with a rational point

4:00pm, CM221

I will give an introduction to the arithmetic of plane curves of degrees 2 and 3, and then compare some conjectures and experiments in the degree 3 case.

Contact anna.felikson@durham.ac.uk for more information about this event.


Dr Michelle Fletcher: Far from the Past? Reading Revelation 18 as Hebrew Bible Imitation

4:15pm, Seminar Room C (D/TH107), Dept. of Theology & Religion, Abbey House, DH1 3RS, Durham

Contact francis.watson@durham.ac.uk for more information about this event.


The Charter of the Forest Public Talk

6:30pm, The Learning Centre, Palace Green Library, Durham, Rob Cowen and Andy Wood

Contact history.reception@durham.ac.uk for more information about this event.