Topological Solitons/Numerical Analysis Seminar: "Adaptation, oscillations, and fluctuations in olfactory sensory neurons"
28 February 2006 13:05 in CM221
"Olfactory sensory neurons are the detector units of the sense of smell. They transduce the initial chemical signal (the odorant molecules) into an electrical signal which is then processed by the brain. I will present mathematical models of the dynamics of this signal transduction process. A deterministic model will be used to show the connection between sensory adaptation and calcium oscillations of an unusual type. It will also serve to illustrate the general mathematical framework of stoichiometric network analysis. To characterize fluctuations and the precision of signal transduction, a simplified stochastic model will then be introduced and studied using a path integral approach. "