Biomathematics Seminar: Viruses and geometry - where symmetry meets function
26 November 2010 15:15 in Mathematical Sciences, CM107
A large number of viruses exhibit icosahedral symmetry in the organisation of the protein containers that encapsulate their genomes. We show here that mathematical insights in virus structure can be used to better understand the structural transitions that viruses must undergo in order to become infectious. We moreover show that geometric insights in virus architecture can be used, in combination with experiment, to completely determine the asymmetric organisation of the linear genomic RNA within a virus particle.