Professor Madeline Eacott
(email at firstname.lastname@example.org)
I am interested in the mechanisms of long-term memory. The modern view sees memory not as a single entity but as a series of interconnected memory systems, each of which has different characteristics and different underlying neural substrates. My work attempts to delineate and understand these different memory processes.
One aspect of my work examines the subdivisions of memory using animals. For example, I have compared the effects of lesions to different parts of the temporal lobes (fornix, perirhinal and postrhinal cortex) in rats in order to elucidate their respective roles in memory. We have found that memory for different aspects of a scene (e.g. what objects were present, where, or in which environment) are all dissociable in memory. This work has resulted in a novel model of episodic-like memory, which allows study of the neural basis of "everyday memory" for events in the rat. My interest in the mechanisms of memory also extends to human memory and our research has recently been extending this work to both adult memory and memory in pre-verbal children. I have also been involved in investigating memory for one's life, from childhood to old age. In particular I am interested in the phenomenon of childhood amnesia and why one cannot remember one's earliest years. The long term goal of all my research is to understand better the memory system in the human and what may go wrong with normal memory in the amnesic patient.
Indicators of Esteem
- 2012: Appointed Associate Editor for the journal Memory :
- 2012: Invited speaker at workshop entitled 'Functional architecture of memory', Bochum, Germany.:
- 2011: Elected Fellow of the British Psychological Society:
- 2011: Symposium organiser and speaker at International Conference on Memory (ICOM-5), York, UK.:
- 2011: Workshop organiser and speaker, 'Cortical and subcortical functions in complex behaviour: A symposium in honour of David Gaffan'. Oxford University, UK:
- 2010: Invited speaker at workshop entitled 'Recognition memory: from proteins to patients', University of Bristol, UK. Fully funded by Wellcome Trust and European Brain and Behaviour Society (EBBS).:
- 2009: Invited speaker at workshop entitled 'The Medial Temporal Lobes', University of Manchester, UK :
- 2007: Invited speaker at European Brain and Behaviour Society (EBBS): Trieste, Italy, Sept 2007.
- 2007: Invited speaker at Experimental Psychology Society (EPS), Cardiff, UK:
- 2006: Invited speaker at the International Conference on Memory (ICOM-4): Sydney, Australia, July 2006
- 2003: Member of the Editorial Advisory Board for Neuroscience & Biobehavioural Reviews:
- Human long-term memory, particularly autobiographical memory and childhood amnesia
- The neuropsychology of memory in animals and people
- Ameen-Ali, K.E., Norman, L.J., Eacott, M.J. & Easton, A. (2017). Incidental context information increases recollection. Learning & Memory 24(3): 136-139.
- Ameen-Ali, K.E., Easton, A. & Eacott, M.J. (2015). Moving beyond standard procedures to assess spontaneous recognition memory. Neuroscience and Biobehavioral Reviews 53: 37-51.
- Grisdale, Emma, Lind, Sophie E., Eacott, Madeline J. & Williams, David M. (2014). Self-referential memory in autism spectrum disorder and typical development: Exploring the ownership effect. Consciousness and Cognition 30: 133-141.
- Eacott, MJ & Easton, A (2012). Remembering the future: The influence of past experience on future behaviour. Learning and Motivation 43: 167-168.
- Easton, A, Webster, LAD & Eacott, MJ (2012). The episodic nature of episodic-like memories. Learning & Memory 19(4): 146-150.
- Easton, A., Fitchett, A., Eacott, M.J. & Baxter, M.G. (2011). Medial septal cholinergic neurons are necessary for context-place memory but not episodic-like memory. Hippocampus 21(9): 1021-1027.
- Jones, EJH Pascalis, O Eacott, MJ & Herbert, JS (2011). Visual recognition memory across contexts. Developmental Science 14(1): 136-147.
- Eacott, MJ & Easton, A (2010). Episodic memory in animals: Remembering which occasion. Neuropsychologia 48(8): 2273-2280.
- Easton, A. & Eacott, M.J. (2010). Recollection of episodic memory within the medial temporal lobe: behavioural dissociations from other types of memory. Behavioural Brain Research 215(2): 310-317.
- Easton, A., Zinkivskay, A. & Eacott, M.J. (2009). Recollection is impaired, but familiarity remains intact in rats with lesions of the fornix. Hippocampus 19(9): 837-843.
- Eacott Madeline J. & Easton Alexander (2007). Mental time travel in the rat: Dissociation of recall and familiarity. Behavioural and brain sciences 30(3): 322-323.
- Eacott, MJ & Easton, A (2007). On familiarity and recall of events by rats. Hippocampus 17: 890-897.
- Norman, G. & Eacott, M.J. (2005). Dissociable effects of lesions to the perirhinal cortex and the postrhinal cortex on memory for context and objects in rats. Behavioral Neuroscience 119(2): 557-566.
- Eacott, MJ., Easton, A. & Zinkivskay, A. (2005). Recollection in an episodic-like memory task in the rat. Learning & Memory 12(3): 221-223.
- Eacott, MJ. & Gaffan EA. (2005). The roles of perirhinal cortex, postrhinal cortex and the fornix in memory for objects, contexts and events in the rat. Quarterly Journal of Experimental Psychology:B 58: 202-217.
- Greenberg, D., Eacott, MJ., Brechin, D. & Rubin, D. (2005). Visual memory loss and autobiographical amnesia: a case study. Neuropsychologia 43: 1493-1502.
- Norman, G. & Eacott, M.J. (2004). Impaired object recognition with increasing levels of feature ambiguity in rats with perirhinal cortex lesions. Behavioural Brain Research 148(1-2): 79-91.
- Eacott, M.J. & Norman, G. (2004). Integrated memory for object, place and context in rats: a possible model of episodic-like memory?. Journal of Neuroscience 24(8): 1948-1953.
- Eacott, M.J., Norman, G. & Gaffan, E.A. (2003). The role of perirhinal cortex in visual discrimination learning for visual secondary reinforcement in rats. Behavioral Neuroscience 117: 1318-1325.
- Norman, G., Brooks, S., Eacott, M.J. & Little, H.J. (2002). Nimdopine prevents scopolomine-induced impairments in object recognition. Journal of Psychopharmacology 16: 153-161.
- Eacott, M.J., Machin, P.E. & Gaffan, E.A. (2001). Elemental and configural visual discrimination learning following lesions to perirhinal cortex in the rat. Behavioural Brain Research 124(1): 55-70.
- Gaffan, E.A., Healey, A.N. & Eacott, M.J. (2000). Objects and positions in visual scenes: effects of perirhinal and postrhinal cortex lesions in the rat. Behavioral Neuroscience
- Gaffan, E.A., Eacott, M.J. & Simpson, E.L. (2000). Perirhinal ablation in rats selectively impairs object identification in a simultaneous visual comparison task. Behavioral Neuroscience 114: 18-31.
- Eacott, M.J. & Crawley, R.A. (1999). Childhood amnesia: on answering questions about very early life events. Memory 7(3): 279-292.
- Crawley, R.A. & Eacott, M.J. (1999). Memory for early life events: Consistency of retrieval of memories over a one year interval. Memory 7(4): 439-460.
- Eacott, M.J. (1999). Memory for the events of early childhood. Current Directions in Psychological Science 8: 46-49.
- Machin, P.E & Eacott, M.J. (1999). Perirhinal cortex lesions and visual discrimination learning in the rat. Psychobiology 27: 470-479.
- Eacott, M.J. (1999). That old familiar feeling: On uniquely identifying the role of the perirhinal cortex. Behavioral and Brain Sciences 22(3): 448-449.
- Eacott, M.J. (1998). "Commentary on ""False memory syndrome and the authority of personal memory claims"".". Philosophy, Psychiatry and Psychology 5: 305-307.
- Eacott, M.J. (1998). Acquisition and retention of concurrent discrimination earning after ablation of perirhinal cortex in the rat. Psychobiology 26: 36-41.
- Simpson, E.L., Gaffan, E.A. & Eacott, M.J. (1998). Rats' object-in-place encoding and the effect of fornix transection. Psychobiology 26: 190-204.
- Eacott, M.J. & Crawley, R.A. (1998). The offset of childhood amnesia: Memory for events that occurred before age 3. Journal of Experimental Psychology: General 127: 22-33.
- Gaffan, E.A. & Eacott, M.J. (1997). Spatial memory impairment in rats with fornix transections is not accompanied by an encoding deficit for directions of objects in space. Behavioral Neuroscience 111: 937-954.
- Parker, A., Eacott, M.J. & Gaffan, D. (1997). The recognition memory deficit caused by mediodorsal thalamic lesions in non-human primates: a comparison with rhinal cortex lesion and normal controls. European Journal of Neuroscience 9: 2423-2431.
- Rushworth, M.F.S., Nixon, P.D., Eacott, M.J. & Passingham, R.E. (1997). Ventral profrontal cortex is not essential for working memory. Journal of Neuroscience 17: 4829-4838.
- Gaffan, E.A. & Eacott, M.J. (1995). A computer-controlled maze environment for testing visual memory in the rat. Journal of Neuroscience Methods 60: 23-37.
- Eacott, M.J. & Heywood, C.A. (1995). Perception and memory: Action and interaction. Critical Reviews in Neurobiology 9: 311-320.
- Gaffan, D. & Eacott, M.J. (1995). Uncinate fascicle section leaves delayed matching to sample intact both with large and small sets. Experimental Brain Research 105: 175-180.
- Gaffan, D. & Eacott, M.J. (1995). Visual learning for an auditory secondary reinforcer is intact after uncinate fascicle section: evidence for the involvement of the corpus striatum. European Journal of Neuroscience 7: 1866-1871.
- Eacott, M.J., Gaffan, D. & Murray, E.A. (1994). Preserved recognition memory for small sets, and impaired stimulus identification for large sets, following rhinal cortex ablations in monkeys. European Journal of Neuroscience 6: 1466-1478.
- Eacott, M.J., Heywood, C.A., Cowey, A. & Gross, C. (1993). Visual discrimination impariments following lesions to the superior temporal sulcus in monkeys are not specific for facial stimuli. Neuropsychologia 31: 609-619.
- Eacott, M.J. & Gaffan, D. (1992). Inferotemporal-frontal disconnection: the uncinate fascicle and visual associative learning in monkeys. European Journal of Neuroscience 4: 1320-1332.
- Eacott, M.J. & Gaffan, D. (1991). The role of monkey inferior parietal cortex in visual discrimination of identity and orientation of shapes. Behavioural Brain Research 46: 95-98.
- Eacott, M.J. & Gaffan, D. (1990). Interhemispheric transfer of visuomotor learning via the anterio corpus callosum of monkeys. Behavioural Brain Research 38: 109-116.
- Eacott, M.J. & Gaffan, D. (1989). Interhemispheric transfer of visual learning in monkeys with intact optic chiasm. Experimental Brain Research 74: 348-352.
- Eacott, M.J. & Gaffan, D. (1989). Reaching to a rewarded visual stimulus: Interhemispheric conflict and hand use in monkeys with forebrain commissurotomy. Brain 112: 1215-1230.
- Gaffan, E.A. & Eacott, M.J. (1986). Memory for feeding in rats' spatial and visual choice behaviour. Quarterly Journal of Experimental Psychology 38B: 285-311.
Available for media contact about:
- Memory and brain function: memory: biological basis of memory
- Memory and brain function: memory: lifespan memory, infantile amnesia, false memories