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Durham University

Department of Chemistry

Publication details for Prof. J.A. Gareth Williams

Jaanus Kruusma, Adam M. Benham, J.A. Gareth Williams & R. Kataky (2006). An introduction to thiol redox proteins in the endoplasmic reticulum and a review of current electrochemical methods of detection of thiols. Analyst 131(4): 459-473.

Author(s) from Durham


This aim of this paper is to expound the complexity of thiol redox systems in the endoplasmic
reticulum of eukaryotic cells to the electroanalytical community. A summary of the state of the art
in electrochemical methods for detection of thiols gives an insight into the challenges that need to
be addressed to bridge the disparity between current analytical techniques and applications in a
‘real’ biological scenario.