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Durham University

Department of Chemistry

Publication details for Prof. Graham Sandford

Hudson, A., Hoose, A., Sandford, G. & Cobb, S.L. (2013). Synthesis of a novel tetra-fluoropyridine containing amino acid and tripeptide. Tetrahedron Letters 54(36): 4865-4867.

Author(s) from Durham


The synthesis of a novel fluoropyridine-containing amino acid from pentafluoropyridine by a nucleophilic substitution process is reported. The orthogonal protecting groups can be manipulated and the fluoropyridine amino acid incorporated into a tripeptide.