Publication details for Prof. Graham SandfordHudson, A., Hoose, A., Sandford, G. & Cobb, S.L. (2013). Synthesis of a novel tetra-fluoropyridine containing amino acid and tripeptide. Tetrahedron Letters 54(36): 4865-4867.
- Publication type: Journal Article
- ISSN/ISBN: 0040-4039 (print)
- DOI: 10.1016/j.tetlet.2013.06.124
- Keywords: Novel amino acid, Pentafluoropyridine, Peptides.
- Further publication details on publisher web site
Author(s) from Durham
The synthesis of a novel fluoropyridine-containing amino acid from pentafluoropyridine by a nucleophilic substitution process is reported. The orthogonal protecting groups can be manipulated and the fluoropyridine amino acid incorporated into a tripeptide.