Staff and Governance
The day-to-day running of IMEMS is the responsibility of the Core Executive Committee, comprising the Director and Associate Directors and the Administrator.
Publication details for Prof. Andrew BeebyAmara, Z., Bellamy, J.F.B., Horvath, R., Miller, S.J., Beeby, A., Burgard, A., Rossen, K., Poliakoff, M. & George, M.W. (2015). Applying green chemistry to the photochemical route to artemisinin. Nature Chemistry 7(6): 489-495.
- Publication type: Journal Article
- ISSN/ISBN: 1755-4330 (print), 1755-4349 (electronic)
- DOI: 10.1038/nchem.2261
- Further publication details on publisher web site
- Durham Research Online (DRO) - may include full text
Author(s) from Durham
Artemisinin is an important antimalarial drug, but, at present, the environmental and economic costs of its semi-synthetic production are relatively high. Most of these costs lie in the final chemical steps, which follow a complex acid- and photo-catalysed route with oxygenation by both singlet and triplet oxygen. We demonstrate that applying the principles of green chemistry can lead to innovative strategies that avoid many of the problems in current photochemical processes. The first strategy combines the use of liquid CO2 as solvent and a dual-function solid acid/photocatalyst. The second strategy is an ambient-temperature reaction in aqueous mixtures of organic solvents, where the only inputs are dihydroartemisinic acid, O2 and light, and the output is pure, crystalline artemisinin. Everything else—solvents, photocatalyst and aqueous acid—can be recycled. Some aspects developed here through green chemistry are likely to have wider application in photochemistry and other reactions.
Full Executive Committee
Our Full Executive Committee is made up of the Core Executive Committee, listed above, plus a number of executive members including:
International Advisory Board
We are extremely fortunate to have be able to call on the help and guidance of colleagues from around the world who help to shape and guide our direction, strategy and international reach. Our current Advisory Board members are: