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Durham Centre for Crop Improvement Technology

Events

DCCIT Director, Ari Sadanandom to chair session at GARNET meeting.

FROM PROTEOME TO PHENOTYPE: ROLE OF POST-TRANSLATIONAL MODIFICATIONS

Society of Experimental Biology and GARNET joint meeting

December 11-13 2017, Edinburgh, United Kingdom

Meeting synopsis

Post-translational protein modifications add a tremendous amount of complexity to cellular proteomes. The large variety of post-translational modifications (PTMs) and their concurrent appearance in proteins dramatically increase the proteome size from mere thousands to the order of millions of possible protein forms. Emerging evidence indicates that in plants crucial regulatory PTMs that control protein function and activity include, amongst others, phosphorylation, ubiquitination, sumoylation, various redox-based modifications, palmitoylation, methylation, ribosylation and acetylation. PTMs intimately regulate a large variety of plant developmental programmes and responses to their environment. Indeed, PTMs are often reversible due to the action of specific enzymes, allowing them to be used as dynamic signalling switches that control protein function. Although PTMs are widely accepted to play indispensable roles in plant developmental and stress responses, how these PTMs generate phenotypical traits is still poorly understood.

We will provide an enhanced understanding and appreciation for the role post-translational protein (PTMs) modifications play in shaping plant phenotypical traits and will be suitable for researchers at any stage in their careers. We particularly welcome early-career PhD students and postdocs, who will benefit most from exposure to the current changing perspective on which factors determine phenotypic traits.

Event information here