Dr Mark Booth, BSc PhD MA(Cantab) ARCS DIC FRSTMH FRGS
Mark joined Durham University in 2008 and is currently Senior Lecturer in Epidemiology and Tropical Health Geography at the School of Medicine, Pharmacy and Health. Mark graduated from Imperial College with a BSc Hons in Zoology. He stayed on to complete a PhD in Biology focusing on the epidemiology and health geography of parasitic infections in developing countries, mainly in Africa. His interest in parasitology continues at Durham with collaborators drawn from within and beyond the University, taking an interdisciplinary approach that combines information from genetics, ecology, geography, ethnography and immunology to yield novel inferences. Simultaneously, Mark has been using his epidemiological background to work in health-related themes of particular relevance to Durham University, including health inequalities in the UK and a broader range of health-related issues in developing countries related to environmental change, including climate change at local, national and international scales. He is actively interested in developing methods of combining biomedical and social research, underpinned by epidemiological principles of study design and inference. Mitigating the effects of changing climates on health through low-carbon transitions in health care settings is a key area of impact-related work.
Mark is a Fellow of both the Royal Geographical Society and the Royal Society for Tropical Medicine and Hygiene. This reflects his background of working at the nexus of epidemiology and tropical health geography.
Healthy Futures Research Project
Mark is currently undertaking follow-up activities related to the EU FP7 funded 'Healthy Futures' project (ENV.2010.1.2.1-1) that concluded its research phase in Dec 2014.
Research on the disease impacts of future environmental changes is a key component of ensuring global wellbeing. At the 2008 World Health Assembly (WHA), member states of the WHO committed themselves to a series of actions aimed at confronting the health risks associated with environmental change. The proposed actions span a range of activities and disciplines and include both basic and applied research. Resolution 61.19 (2008) calls for the development of improved decision-support, surveillance and monitoring tools for assessing vulnerability to and health impacts of infectious diseases (WHO 2009). The 'Healthy Futures' project is adressing this resolution through a multidisciplinary consortium that will examine the influence of a wide range of environmental, socio-economic and demographic factors on transmission of schistosomiasis, rift valley fever and malaria.
Universal Sustainable Habitat Development
The UN General Assembly has declared 2014-24 as the decade of ‘Sustainable Energy for All’. This idea is especially important in Africa where approx. 600 million people rely on charcoal, firewood, diesel and/or kerosene for heat and light and/or powering electrical devices. Poor health, poverty, low-quality education and disempowerment are all outcomes associated with lack of access to sustainable energy. Delivering solar power is part of the solution but there is a need to consider this in the wider context of sustainable development.
The Universal Sustainable Habitat Development (USHD) is a demand-driven, off-grid and scalable concept that involves building new, or rehabilitating existing, community structures (schools, community centres, health centres, domestic housing, sports grounds etc.) and providing each facility with an integrated array of renewable resources (energy, water, bio-gas) to enable a sustainable environment. The main energy source in each building is likely to be sunlight – captured through photovoltaic panels (solar PV), supplemented by wind and geo-thermal resources where available and required. Also integrated into each building will be water-harvesting facilities, anaerobic digestion units, heat exchange mechanisms and solar-thermal equipment. The internal space will be designed according to wishes of the key-stakeholders and may be focused on one domain (e.g. school) or may cover multiple domains (e.g. community centre). A major component of the concept is the Monitoring & Evaluation, Training, Research and Evaluation (METRE) programme that aims to measure inputs, outputs, outcomes and impacts associated with USHD facilities. The USHD offers a highly flexible and cost-effective solution to providing vulnerable communities with sustainable energy as a catalyst for empowerment, good health, high-quality education and economic development.
More information available here: http://www.dur.ac.uk/dei/projects/ushd
Healthy Futures Atlas
This interactive, online tool will help you consider how vulnerable populations in East Africa might remain at risk of infections from malaria, schistosomiasis and rift valley fever as a result of global warming. Use the atlas to explore how different vulnerabilty indicators may contribute to the overall future risk to populations living in specfic areas. Click on the link below to access the Atlas
Ruth First Educational Trust
Mark sits on the Executive Committee for the Trust, which raises money to bring scholars from Southern Africa to Durham for postgraduate (Masters level) studies. More information about the Trust is available from the link below:
Dr Booth co-supervises the following PhD students:
Mildred Ajebon (with Prof Sarah Curtis) - Multiple deprivations and maternal health care in Nigeria
Chandika Shrestha (with Dr Chris Dunn) - The geography of post-disaster mental health and well-being: spatial patterning of vulnerability and resilience factors in Nepal after Gorkha Earthquake, 2015
- Cable, J., Barber, I., Boag, B., Ellison, A.R., Morgan, E.R., Murray, K., Pascoe, E.L., Sait, S.M., Wilson, A.J. & Booth, M. (2017). Global change, parasite transmission and disease control: lessons from ecology. Philosophical Transactions of the Royal Society B: Biological Sciences 372(1719): 20160088.
- Wilson, A.J., Morgan, E.R., Booth, M., Norman, R., Perkins, S.E., Hauffe, H.C., Mideo, N., Antonovics, J., McCallum, H. & Fenton, A. (2017). What is a vector?. Philosophical Transactions of the Royal Society B: Biological Sciences 372(1719): 20160085.
- Stensgaard, A., Booth, M., Nikulin, G. & McCreesh, N. (2016). Combining process-based and correlative models improves predictions of climate change effects on Schistosoma mansoni transmission in eastern Africa. Geospatial Health 11(1s): 406.
- Makwela-Wali, Khaiko & Booth, Mark (2016). Innovating the Built Environment to Accelerate Sustainable Development – The Integrated Habitat Approach. Energy Procedia 93: 61-65.
- Ocampo, D. & Booth, M. (2016). The application of evolutionary medicine principles for sustainable malaria control: a scoping study. Malaria Journal 15(1): 383.
- Braun, T., Bambra, C.L., Booth, M., Kasim, A. & Milne, E. (2015). Better health at work? An evaluation of the effects and cost benefits of a structured workplace health improvement programme in reducing sickness absence. Journal of Public Health 37(1): 138-142.
- McCreesh, N., Nikulin, G. & Booth, M. (2015). Predicting the effects of climate change on Schistosoma mansoni transmission in eastern Africa. Parasites & Vectors 8(1): 4.
- Houghton, L.C., Cooper, G.D., Bentley, G.R., Booth, M., Chowdhury, O.A., Troisi, R., Ziegler, R.G., Hoover, R.N. & Katki, H.A. (2014). A migrant study of pubertal timing and tempo in British-Bangladeshi girls at varying risk for breast cancer. Breast Cancer Research 16(6): 469.
- Houghton, L.C., Cooper, G.D., Booth, M., Chowdhury, O.A., Troisi, R., Ziegler, R.G., Katki, H.A., Hoover, R.N. & Bentley, G.R. (2014). Childhood Environment Influences Adrenarcheal Timing among First-Generation Bangladeshi Migrant Girls to the UK. PLoS ONE 9(10): e109200.
- McCreesh, N. & Booth, M. (2014). Effect of water temperature and population density on the population dynamics of Schistosoma mansoni intermediate host snails. Parasites & Vectors 7: 503.
- Sarfo, F.S., Sarfo, M.A., Kasim, A., Phillips, R., Booth, M. & Chadwick D. (2014). Long-term effectiveness of first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in Ghana. Journal of Antimicrobial Chemotherapy 69(1): 254-261.
- Warren, J., Bambra, C., Kasim, A., Garthwaite, K., Mason, J. & Booth, M. (2014). Prospective pilot evaluation of the effectiveness and cost-utility of a "health first" case management service for long-term Incapacity Benefit recipients. Journal of Public Health 36(1): 117-125.
- McCreesh, N. & Booth, M. (2014). The effect of increasing water temperatures on Schistosoma mansoni transmission and Biomphalaria pfeifferi population dynamics: an agent-based modelling study. PLoS ONE 9(7): e101462.
- McCreesh, N. & Booth, M. (2014). The Effect of Simulating Different Intermediate Host Snail Species on the Link between Water Temperature and Schistosomiasis Risk. PLoS ONE 9(7): e87892.
- McCreesh, Nicky & Booth, Mark (2013). Challenges in predicting the effects of climate change on Schistosoma mansoni and Schistosoma haematobium transmission potential. Trends in Parasitology 29(11): 548-555.
- Kariuki, H.C., Madsen, H., Ouma, J.H., Butterworth, A.E., Dunne, D.W., Booth, M., Kimani, G., Mwatha, J.K., Muchiri, E. & Vennervald, B.J. (2013). Long term study on the effect of mollusciciding with niclosamide in streamhabitats on the transmission of schistosomiasis mansoni after community-basedchemotherapy in Makueni District, Kenya. Parasites & Vectors 6(1): 107.
- Naraghi, K., Booth, M., Russell, A.J. & van Laar, J.M. (2011). Determination of smoking status of rheumatoid arthritis patients by means of a self-reported questionnaire and serum cotinine assay: a cross-sectional study. Annals of the Rheumatic Diseases
- Stothard, JR, Chiodini, P & Booth, M (2011). Progress in paediatric parasitology: a preface to a topic focusing on ever younger subjects. Parasitology 138(12): 1453-8.
- de Moira, Angela Pinot, Kabatereine, Narcis B., Dunne, David W. & Booth, Mark (2011). Understanding Ethnic Differences in behaviour relating to schistosoma mansoni re-infection after mass treatment. JOURNAL OF BIOSOCIAL SCIENCE 43(2): 185-209.
- de Moira, Angela Pinot, Fulford, Anthony J.C., Kabatereine, Narcis B., Ouma, John H., Booth, Mark & Dunne, David W. (2010). Analysis of Complex Patterns of Human Exposure and Immunity to Schistosomiasis mansoni: The Influence of Age, Sex, Ethnicity and IgE. PLoS Neglected Tropical Diseases 4(9): e820.
- S. Wilson, B.J. Vennervald, H. Kadzo, E. Ireri, C. Amaganga, M. Booth, H.C. Kariuki, J.K. Mwatha, G. Kimani, J.H. Ouma, E. Muchiri & D.W. Dunne (2010). Health implications of chronic hepatosplenomegaly in Kenyan school-aged children chronically exposed to malarial infections and Schistosoma mansoni. Trans R Soc Trop Med Hyg 104(2): 110-6.
- Woodburn,PW, Muhangi,L, Hillier,S, Ndibazza,J, Namujju,PB, Kizza,M, Ameke,C, Omoding,NE, Booth,M & Elliott,AM (2009). Risk Factors for Helminth, Malaria, and HIV Infection in Pregnancy in Entebbe, Uganda. PLoS Neglected Tropical Diseases 3(6): e473.
- S. Wilson, F.M. Jones, J.K. Mwatha, G. Kimani, M. Booth, H.C. Kariuki, B.J. Vennervald, J.H. Ouma, E. Muchiri & D.W. Dunne (2008). Hepatosplenomegaly is associated with low regulatory and Th2 responses to schistosome antigens in childhood schistosomiasis and malaria coinfection. Infect Immun 76(5): 2212-8.
- M. Booth, A. Graham & M. Viney (2008). Parasitic co-infections: challenges and solutions. Parasitology 135(7): 749-749.
- S.D. Hillier, M. Booth, L. Muhangi, P. Nkurunziza, M. Khihembo, M. Kakande, M. Sewankambo, R. Kizindo, M. Kizza, M. Muwanga & A.M. Elliott (2008). Plasmodium falciparum and Helminth Coinfection in a Semiurban Population of Pregnant Women in Uganda. Journal of Infectious Diseases 198(6): 920-927.
- S. Wilson, M. Booth, F.M. Jones, J.K. Mwatha, G. Kimani, H.C. Kariuki, B.J. Vennervald, J.H. Ouma, E. Muchiri & D.W. Dunne (2007). Age-adjusted Plasmodium falciparum antibody levels in school-aged children are a stable marker of microgeographical variations in exposure to Plasmodium infection. BMC Infect Dis 7: 67.
- S. Wilson, B.J. Vennervald, H. Kadzo, E. Ireri, C. Amaganga, M. Booth, H.C. Kariuki, J.K. Mwatha, G. Kimani, J.H. Ouma, E. Muchiri & D.W. Dunne (2007). Hepatosplenomegaly in Kenyan schoolchildren: exacerbation by concurrent chronic exposure to malaria and Schistosoma mansoni infection. Trop Med Int Health 12(12): 1442-9.
- A. Pinot de Moira, A.J. Fulford, N.B. Kabatereine, F. Kazibwe, J.H. Ouma, D.W. Dunne & M. Booth (2007). Microgeographical and tribal variations in water contact and Schistosoma mansoni exposure within a Ugandan fishing community. Trop Med Int Health 12(6): 724-35.
- D.W. Dunne, B.J. Vennervald, M. Booth, S. Joseph, C.M. Fitzsimmons, P. Cahen, R.F. Sturrock, J.H. Ouma, J.K. Mwatha, G. Kimani, H.C. Kariuki, F. Kazibwe, E. Tukahebwa & N.B. Kabatereine (2006). Applied and basic research on the epidemiology, morbidity, and immunology of schistosomiasis in fishing communities on Lake Albert, Uganda. Trans R Soc Trop Med Hyg 100(3): 216-23.
- M. Booth, M.A. Shaw, D. Carpenter, S. Joseph, N.B. Kabatereine, H.C. Kariuki, J.K. Mwatha, F.M. Jones, B.J. Vennervald, J.H. Ouma & D.W. Dunne (2006). Carriage of DRB1*13 is associated with increased posttreatment IgE levels against Schistosoma mansoni antigens and lower long-term reinfection levels. J Immunol 176(11): 7112-8.
- F. Kazibwe, B. Makanga, C. Rubaire-Akiiki, J. Ouma, H.C. Kariuki, N.B. Kabaterine, M. Booth, B.J. Vennervald, R.F. Sturrock & S. R (2006). Ecology of Biomphalaria (Gastropoda: Planorbidae) in Lake Albert, Western Uganda: snail distributions, infection with schistosomes and temporal associations with environmental dynamics. Hydrobiologia 568(1): 433 - 444.
- C.M. Reimert, C.M. Fitzsimmons, S. Joseph, J.K. Mwatha, F.M. Jones, G. Kimani, K.F. Hoffmann, M. Booth, N.B. Kabatereine, D.W. Dunne & B.J. Vennervald (2006). Eosinophil activity in Schistosoma mansoni infections in vivo and in vitro in relation to plasma cytokine profile pre- and posttreatment with praziquantel. Clin Vaccine Immunol 13(5): 584-93.
- M. Booth (2006). The role of residential location in apparent helminth and malaria associations. Trends Parasitol 22(8): 359-62.
- B. Vennervald, M. Booth, A.E. Butterworth, C.H. Kariuki, H. Kadzo, E. Ireri, C. Amaganga, K. Gachuhi, L.C. Kenty, J.K. Mwatha, J.H. Ouma & D.W. Dunne (2005). Regression of hepatosplenomegaly in Kenyan school-aged children after praziquantel treatment and in the absence of re-infection by Schistosoma mansoni. Transactions of the Royal Society of Tropical Medicine and Hygiene 99(2): 150-60.
- S. Joseph, F.M. Jones, G. Kimani, J.K. Mwatha, T. Kamau, F. Kazibwe, J. Kemijumbi, N.B. Kabatereine, M. Booth, H.C. Kariuki, J.H. Ouma, B.J. Vennervald & D.W. Dunne (2004). Cytokine production in whole blood cultures from a fishing community in an area of high endemicity for Schistosoma mansoni in Uganda: the differential effect of parasite worm and egg antigens. Infection and Immunity 72(2): 728-34.
- B.J. Vennervald, L.C. Kenty, A.E. Butterworth, C.H. Kariuki, H. Kadzo, E. Ireri, C. Amaganga, K. Gachuhi, J.K. Mwatha, A. Otedo, M. Booth, J.H. Ouma & D.W. Dunne (2004). Detailed clinical and ultrasound examination of children and adolescents in a Schistosoma mansoni endemic area in Kenya: hepatosplenic disease in the absence of portal fibrosis. Tropical Medicine and International Health 9(4): 461 - 470.
- M. Booth, B.J. Vennervald, A.E. Butterworth, H.C. Kariuki, A. Clifford, G. Kimani, J.K. Mwatha, A. Otedo, J.H. Ouma & D.W. Dunne (2004). Exposure to malaria affects the regression of hepatosplenomegaly after treatment for Schistosoma mansoni infection in Kenyan children. BMC Medicine 2(1): 36.
- M. Booth, B.J. Vennervald, H. Kadzo, F. Kazibwe, J.H. Ouma, K. Gachuhi, N.B. Kabatereine & D.W. Dunne (2004). Hepatosplenic morbidity in two neighbouring communities in Uganda with high levels of Schistosoma mansoni infection but very different durations of residence. Transactions of the Royal Society of Tropical Medicine and Hygiene 98: 125 - 136.
- Booth, M., Vennervald, B.J., Kenty, L.C., Butterworth, A.E., Kariuki, C.H., Kadzo, H., Ireri, E., Amaganga, C., Gachuhi, K., Mwatha, J.K., Otedo, A., Ouma, J. & Dunne, D.W. (2004). Micro-geographical variation in exposure to Schistosoma mansoni and malaria, and exacerbation of splenomegaly in Kenyan school-aged children. BMC Infectious Diseases 4: 13.
- M. Booth, J.K. Mwatha, S. Joseph, F.M. Jones, H. Kadzo, E. Ireri, F. Kazibwe, J. Kemijumbi, C.H. Kariuki, K. Gachuhi, J.H. Ouma, N.B. Kabatereine, B.J. Vennervald & D.W. Dunne (2004). Peri-portal fibrosis in human Schistosoma mansoni infection is associated with low IL-10, low IFNg, high TNFa or low RANTES, depending on age and gender. Journal of Immunology 172: 1295 - 1303.
- M. Booth & D.W. Dunne (2004). Spatial awareness in parasite immuno-epidemiology. Parasite Immunol 26(11-12): 499-507.
- M. Booth, P. Vounatsou, E.K. N'Goran, M. Tanner & J. Utzinger (2003). The influence of sampling effort and the performance of the Kato-Katz technique in diagnosing Schistosoma mansoni and hookworm co-infections in rural Cote d'Ivoire. Parasitology 127: 525 - 531.
- C.W. Naus, M. Booth, F.M. Jones, J. Kemijumbi, B.J. Vennervald, C.H. Kariuki, J.H. Ouma, N.B. Kabatereine & D.W. Dunne (2003). The relationship between age, sex, egg-count and specific antibody responses against Schistosoma mansoni antigens in a Ugandan fishing community. Tropical Medicine and International Health 8(6): 561-8.
- J. Utzinger, P. Vounatsou, E.K. N'Goran, M. Tanner & M. Booth (2002). Reduction in the prevalence and intensity of hookworm infections after praziquantel treatment for schistosomiasis infection. International Journal for Parasitology 32(6): 759-65.
- T. Smith, J.L. Hii, B. Genton, I. Muller, M. Booth, N. Gibson, A. Narara & M.P. Alpers (2001). Associations of peak shifts in age--prevalence for human malarias with bednet coverage. Transactions of The Royal Society of Tropical Medicine and Hygiene 95(1): 1-6.
- J. Utzinger, M. Booth, E.K. N'Goran, I. Muller, M. Tanner & C. Lengeler (2001). Relative contribution of day-to-day and intra-specimen variation in faecal egg counts of Schistosoma mansoni before and after treatment with praziquantel. Parasitology 122(Pt 5): 537-44.
- J. Utzinger, E.K. N'Goran, Y.A. Ossey, M. Booth, M. Traore, K.L. Lohourignon, A. Allangba, L.A. Ahiba, M. Tanner & C. Lengeler (2000). Rapid screening for Schistosoma mansoni in western Cote d'Ivoire using a simple school questionnaire. Bulletin of the World Health Organization 78(3): 389-98.
- S.H. Xiao, M. Booth & M. Tanner (2000). The prophylactic effects of artemether against Schistosoma japonicum infections. Parasitology Today 16(3): 122-6.
- S. Brooker, M. Booth & H. Guyatt (1999). Comparisons of schistosome and geohelminth infection prevalences in school-aged children from selected areas of Africa: implications for rapid assessment and combined control. Transactions of The Royal Society of Tropical Medicine and Hygiene 93(2): 125-6.
- M. Booth, D.A. Bundy, M. Albonico, H.M. Chwaya, K.S. Alawi & L. Savioli (1998). Associations among multiple geohelminth species infections in schoolchildren from Pemba Island. Parasitology 116 ( Pt 1): 85-93.
- C. Pervilhac, H. Mshinda, J. Utzinger, M. Booth & M. Tanner (1998). Experiences with a multi-sectorial operation research programme for control of schistosomiasis in a Tanzanian district. Afr J Health Sci 5(3-4): 153-61.
- J. Guo, M. Booth, J. Jenkins, H. Wang & M. Tanner (1998). Field activity cost estimates for the first 3 years of the World Bank Loan Project for schistosomiasis control in China. Southeast Asian Journal of Tropical Medicine and Public Health 29(4): 706-13.
- A.G. Ross, Y. Li, M. Booth, A.C. Sleigh, G.M. Williams & D.P. McManus (1998). Five year impact of chemotherapy on morbidity attributable to Schistosoma japonicum infection in the Dongting Lake region. Tropical Medicine and International Health 3(10): 837-41.
- J.D. Charlwood, T. Smith, E. Lyimo, A.Y. Kitua, H. Masanja, M. Booth, P.L. Alonso & M. Tanner (1998). Incidence of Plasmodium falciparum infection in infants in relation to exposure to sporozoite-infected anophelines. American Journal of Tropical Medicine and Hygiene 59(2): 243-51.
- M. Booth (1998). The application of attributable risk analysis in helminth epidemiology. Parasitology Today 14(12): 497 - 500.
- M. Booth, C. Mayombana & P. Kilima (1998). The population biology and epidemiology of schistosome and geohelminth infections among schoolchildren in Tanzania. Transactions of The Royal Society of Tropical Medicine and Hygiene 92(5): 491-5.
- M. Booth, C. Mayombana, H. Machibya, H. Masanja, P. Odermatt, J. Utzinger & P. Kilima (1998). The use of morbidity questionnaires to identify communities with high prevalences of schistosome or geohelminth infections in Tanzania. Transactions of The Royal Society of Tropical Medicine and Hygiene 92(5): 484-90.
- M. Booth, Y. Li & M. Tanner (1996). Helminth infections, morbidity indicators and schistosomiasis treatment history in three villages, Dongting Lake region, PR China. Tropical Medicine and International Health 1(4): 464-74.
- M. Booth, H.L. Guyatt, Y. Li & M. Tanner (1996). The morbidity attributable to Schistosoma japonicum infection in 3 villages in Dongting Lake region, Hunan province, PR China. Tropical Medicine and International Health 1(5): 646-54.
- M. Booth & D.A. Bundy (1995). Estimating the number of multiple-species geohelminth infections in human communities. Parasitology 111 ( Pt 5): 645-53.
- M.S. Chan, H.L. Guyatt, D.A. Bundy, M. Booth, A.J. Fulford & G.F. Medley (1995). The development of an age structured model for schistosomiasis transmission dynamics and control and its validation for Schistosoma mansoni. Epidemiology and Infection 115(2): 325-44.
- M. Booth & D.A. Bundy (1992). Comparative prevalences of Ascaris lumbricoides, Trichuris trichiura and hookworm infections and the prospects for combined control. Parasitology 105 ( Pt 1): 151-7.
- Booth, M. (2016). Why evolution must be at the centre of fighting parasitic infections. www.theconversation.com
- Booth, M (2015). 'An integrated, sustainable fix is key to solving Africa's energy woes'. www.theconversation.com
- Booth, M. (2015). There’s a fly in the ointment of solar-powered LED lighting. www.theconversation.com
- Mark Booth (2015). Tropical worms: they infect a third of the planet, so why aren’t we doing more?. www.theconversation.com
- Booth, M. (2012). Two and a half cheers for Bill Gates. New Statesman