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Durham University

Research & business

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Biomolecular Interactions

A research group of the Department of Biosciences.

Bioscience Embedded within Chemistry.

Biomolecular interactions, including contacts between biological macromolecules (protein/protein or protein/nucleic acids) and protein-ligand interactions are central to biochemistry. This grouping addresses fundamental questions concerning, for example, the recognition of DNA by bacterial proteins, the biophysical basis of allostery and the supply of metals to proteins. Multiple projects aim to identify targets for new antimicrobial (and antiviral) compounds and typically exploit a wide range of chemical, biochemical, and biophysical methods.

More than half of the members of the group are located in embedded biology laboratories within the Department of Chemistry and PIs have close interactions with the Bioactive Chemistry and Synthesis grouping in chemistry.

Group Coordinator: Dr Paul Denny

Academic Staff: Dr Tim R BlowerProf Martin CannDr Peter Chivers, Dr Paul Denny, Dr Karrera Djoko, Dr Sushma Grellschied, Dr Ehmke Pohl, Prof. Nigel RobinsonDr Martin Schröder, Dr Gary Sharples, Prof A Walmsley.

Affiliates: Dr Adam Benham, Dr P Chazot, Dr Tony Fawcett, Professor John A. Gatehouse, Dr Martin Goldberg, Prof Keith Lindsey, Dr J Liu, Dr David Weinkove

Research Areas

  • Biomolecular interactions and protein-ligand interactions play a central role in all our research interest

Staff

Academic Staff

Publications by staff in this group

Journal Article