Dr Tessa Young - all publications

Journal Article

• Young, Tessa R., Wedd, Anthony G. & Xiao, Zhiguang (2018). Evaluation of Cu(I) binding to the E2 domain of the amyloid precursor protein – a lesson in quantification of metal binding to proteins via ligand competition. Metallomics 10(1): 108-119.
• Young, Tessa R., Pukala, Tara L., Cappai, Roberto, Wedd, Anthony G. & Xiao, Zhiguang (2018). The Human Amyloid Precursor Protein Binds Copper Ions Dominated by a Picomolar Affinity Site in the Helix-Rich E2 Domain. Biochemistry 57(28): 4165-4176.
• Yako, Nineveh, Young, Tessa R., Cottam Jones, Jade M., Hutton, Craig A., Wedd, Anthony G. & Xiao, Zhiguang (2017). Copper binding and redox chemistry of the Aβ16 peptide and its variants: insights into determinants of copper-dependent reactivity. Metallomics 9(3): 278-291.
• Young, Tessa R., Wijekoon, Chathuri J. K., Spyrou, Benjamin, Donnelly, Paul S., Wedd, Anthony G. & Xiao, Zhiguang (2015). A set of robust fluorescent peptide probes for quantification of Cu(II) binding affinities in the micromolar to femtomolar range. Metallomics 7(3): 567-578.
• Wijekoon, Chathuri J. K., Young, Tessa R., Wedd, Anthony G. & Xiao, Zhiguang (2015). CopC Protein from Pseudomonas fluorescens SBW25 Features a Conserved Novel High-Affinity Cu(II) Binding Site. Inorganic Chemistry 54(6): 2950-2959.
• Young, Tessa R., Kirchner, Angie, Wedd, Anthony G. & Xiao, Zhiguang (2014). An integrated study of the affinities of the Aβ16 peptide for Cu(I) and Cu(II): implications for the catalytic production of reactive oxygen species. Metallomics 6(3): 505-517.
• Leong, Su Ling, Young, Tessa R., Barnham, Kevin J., Wedd, Anthony G., Hinds, Mark G., Xiao, Zhiguang & Cappai, Roberto (2014). Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function. Metallomics 6(1): 105-116.