Durham University

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Dr Karrera Djoko, PhD (Chemistry)

Assistant Professor in the Department of Biosciences
Visiting Assistant Professor in the Department of Chemistry

Contact Dr Karrera Djoko (email at karrera.djoko@durham.ac.uk)

Research Program

Trace nutrient metal ions (iron, manganese, zinc, copper) are essential for the function of nearly half of all proteins but they are toxic to cells if present in excess or if inserted into the wrong sites. The battle to control metal availability is now recognised as a key component of host-pathogen interactions in so-called “Nutritional Immunity” and there is growing interest in developing agents that manipulate nutrient metal level and location as new antimicrobial therapeutics.

Key questions that drive our research program are:

1. How does host-imposed, metal-linked nutritional immunity impact bacterial physiology?

2. How do bacteria adapt to the effects of nutritional immunity?

3. When/where in the host do bacterial pathogens encounter metal ions?

4. Can we learn from nature and manipulate metal levels and locations as new antibacterial approaches?

Research Groups

Department of Biosciences

Wolfson Research Institute for Health and Wellbeing

Research Interests

  • Metals in microbiology
  • Infectious diseases
  • Microbial physiology
  • Antimicrobial resistance
  • Antimicrobial development

Selected Publications

Chapter in book

Journal Article

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Supervises