Publication details for Professor Martin CannBretonnière, Y., Cann, M.J., Parker, D. & Slater, R. (2002). Ratiometric probes for hydrogencarbonate analysis in intracellular or extracellular environments using europium luminescence. Chemical Communications 2002(17): 1930-1931.
- Publication type: Journal Article
- ISSN/ISBN: 1359-7345, 1364-548X
- DOI: 10.1039/B206286K
- Further publication details on publisher web site
Author(s) from Durham
A series of six, cationic, zwitterionic and anionic Eu complexes has been examined for the analysis of hydrogencarbonate concentration in the intracellular and extracellular ranges; an anionic complex incorporating three glutarate residues and a sensitising acridone chromophore (lambda exc = 410 nm) exhibits a 69% change in the intensity ratio of the 618/588 nm Eu emission bands between 5 and 15 mM HCO3- in a cell lysate medium.