Dr Jun Jie Wu, MSc (Oxon) DPhil (Oxon)
(email at firstname.lastname@example.org)
Dr Wu is an Associate Professor (Reader) in Bioengineering. Her research interests are in the areas of bone, ocular tissue, numerical modelling of natural and synthetic polymers, biomaterials for prostheses bearing surfaces, and functional tissue engineering.
She obtained her MSc in Computer Science (Parallel Computing) from Oxford University Computing Laboratory and a DPhil from Department of Engineering Science at Oxford University, where she was a Career Development Fellow before joining the University of Durham.
Since joining Durham, she has held and is currently holding research fundings as Principal investigator in Biomaterials, Modelling, Tissue engineering and Biotribology for a number of recent projects.
She is teaching/has taught the following courses: Bioengineering, Materials, Polymers, Metals and Alloys, Fluid Mechanics, Engineering Design, Dynamic System Modelling and Engineering drawing.
EPSRC Funding on Novel Diagnostic Tool for Tissue Damage (total £1.28 million)
Leverhulme Grant on Lens Modelling
National Osteoporosis Society Funding on Hip Fracture
Medical Research Council Strategic Award on Biomaterials
Royal Academy of Engineering Funding on Tissue Engineering
EPSRC Funding on Novel Approaches for Improving UHMWPE Wear and Fatigue Properties in Knee Joints
EPSRC Funding on Adsorption and Adhesion on Semi-Crystalline Polymers
Technology Strategy Board Funding on Novel Hip
Biomet Funding on Next Generation Joints
Morgan Advanced Ceramics Funding on Orthopaedic Arthroplasty
Biomet Funding on Structural and Biotribological Investigations of Ceramic-on-Ceramic Hip Joints
EPSRC and Biomet Funding on Structural and Biotribological Investigations of Ceramic-on-Metal Hip Joints
Bio-Energy, Energy Efficiency and Water PhD Projects available
Project 1 Improving Energy Efficiency in a Modern Water Factory
The combination of a water reclamation plant (such as NEW Water plants) with seawater desalination are being considered in many large developing mega cities around the world. Away from coasts water recycle will become even more important. We have developed a novel hybrid process that needs to be evaluated alongside other process schemes for various water usage scenarios. The process design algorithms available include our recently published methodology for the sizing of forward osmosis plants. This project has international and industrial technical support.
Project 2 Sustainable energy: Potential in Osmotic Power
Just as the separation of salty water into fresh water and a brine requires energy so the mixing of a brine and fresh water can (if it is done in a controlled manner) produce energy. Originally proposed in a Science paper around 50 years ago, there has been much research into osmotic power (variously called pressure retarded osmosis or generically “Blue Energy”). Now that membranes have been tailored for this application and greatly improved the limits to performance are no longer governed by the membrane properties alone. The project will develop a performance envelope based upon various combinations of membrane properties and system hydrodynamics.
Project 3 Improving Energy Efficiency of Aerobic Digestion
Successful operation of Aerobic Digestion in cold weather is challenging. We have discussed a novel approach with the water industry and the research question is: can our approach boost the growth rate of the microbial biomass?
Project 4 Solar Driven, Gravity Driven and Other ‘Low Energy’ Potable Water Treatment Processes
Drinking water is scarce in many parts of the world were solar energy is plentiful. The project boundary is such as to exclude those processes with a relatively high demand of electrical power. Many processes have been labelled as “emerging processes” for the last decade. After an initial survey three processes from different areas will be evaluate to determine if any have break through potential.
Project 5 Potable Water Treatment Using Direct Flow Membrane Modules: Design of Hollow Fibre Modules
Membranes are now a huge part of the water market, especially since the advent of the Direct Flow modules that uses far less energy than crossflow modules. These are hollow fibre modules with about 10 000 fibres per module. We have developed a model for side take-off that successful captures industrial practice. Other variants are being developed. Now as non-uniform distribution of fibres is intrinsic to the manufacturing process research on the effect of non-uniformity should now be included. We are progressing this work with industrial technical support.
Project 6 Potable Water Treatment Using Direct Flow Membrane Modules: Influence of Cleaning Chemicals Upon Fibre Integrity.
Successful operation of the Direct Flow format is dependent upon the inclusion of periodic backwashes including chemically enhanced backwashes. As the latter may be a few times per day the membranes are exposed regularly to oxidising chemicals. We have piloted a technique for performing accelerated tests and obtained excellent preliminary results. This project has industrial technical support.
- Hanusch, B. C., Tuck, S. P., McNally, R. J. Q., Wu, J. J., Datta, H. K. & Francis, R. M. (2017). Does regional loss of bone density explain low trauma distal forearm fractures in men (The Mr F study)?. Osteoporosis International
- Mondal, S., Field, R. W. & Wu, J. J. (2017). Novel Approach for Sizing Forward Osmosis Membrane Systems. Journal of Membrane Science 541: 321-328.
- Wu, X., Field, R., Wu, J. J. & Zhang, K. (2017). Polyvinylpyrrolidone modified graphene oxide as a modifer for thin film composite forward osmosis membranes. Journal of Membrane Science 540: 251-260.
- Liu, S., Zhang, M., Fang, F., Cui, L., Wu, J.J., Field, R. & Zhang, K. (2016). Biogenic silver nanocomposite TFC nanofiltration membrane with antifouling properties. Desalination and Water Treatment 57(23): 10560-10571.
- Wu, J.J., Wu, W., Tholozan, F.M., Saunter, C.D., Girkin, J.M. & Quinlan, R.A. (2015). A dimensionless ordered pull-through model of the mammalian lens epithelium evidences scaling across species and explains the age-dependent changes in cell density in the human lens. Journal of The Royal Society Interface 12(108): 20150391.
- Brown, P.S., Talbot, E.L., Wood, T.J., Egan, M.J., Wu, J.J., Sainic, K., Kumarc, N., Bain, C.D. & Badyal, J.P.S. (2015). Controlling picolitre droplet impact dynamics by tailoring the solid subsurface. Colloids and Surfaces A: Physicochemical and Engineering Aspects 481: 215-221.
- Liu, S., Fang, F., Wu, J.J. & Zhang, K. (2015). The anti-biofouling properties of thin-film composite nanofiltration membranes grafted with biogenic silver nanoparticles. Desalination 375: 121-128.
- Alshryda, S., Mason, J.M., Sarda, P., Lou, T., Stanley, M., Wu, J.J. & Unsworth, A. (2015). The effect of tranexamic acid on artificial joint materials a biomechanical study (the bioTRANX study). Journal of orthopaedics and traumatology 16(1): 27-34.
- Wu, W., Tholozan, F.M., Goldberg, M.W., Bowen, L., Wu, J.J. & Quinlan, R.A (2014). A gradient of matrix-bound FGF-2 and perlecan is available to lens epithelial cells. Experimental Eye Research 120: 10-14.
- Younis S, Walker J, Wu JJ, Datta HK & Tuck SP (2014). ZIC1 and SOST immunohistochemistry staining of osteocytes and osteoblasts in femoral head tissue. Osteoporosis International 25: 64.
- Lal S, Salpingidou G & Wu JJ (2013). Factors influencing wear particle size, morphology and cell viability. Proceedings of the 6th International UHMWPE Meeting
- Field R. & Wu, J.J. (2013). Mass transfer limitations. Desalination 318: 118-124.
- Field, R., Wu, H. & Wu, J.J. (2013). Multiscale Modeling of Membrane Distillation: Some Theoretical Considerations. Industrial & Engineering Chemistry Research 52(26): 8822-8828.
- Wang, Q., Wu, J.J., Unsworth, A., Briscoe, A., Jarman-Smith, M., Lowry, C., Simpson, D. & Collins, S. (2012). Biotribological study of large diameter ceramic-on-CFR-PEEK hip joint including fluid uptake, wear and frictional heating. Journal of Materials Science: Materials in Medicine 23(6): 1533-1542.
- Douillard, T., Chevalier, J., Descamps-Mandine, A., Warner, I., Galais, Y., Whitaker, P., Wu, J.J. & Wang, Q.Q. (2012). Comparative ageing behaviour of commercial, unworn and worn 3Y-TZP and zirconia-toughened alumina hip joint heads. Journal of the European Ceramic Society 32(8): 1529-1540.
- Caldwell, S., Johnson, D., Didsbury, M., Murray, B., Wu, J.J., Przyborski, S. & Cameron, N.R. (2012). Degradable emulsion-templated scaffolds for tissue engineering from thiol– ene photopolymerisation. Soft Matter 8(40): 10344-10351.
- Wu JJ (2012). Is Vitamin E Stabilised UHMWPE the Future Material for TKA?. Journal of Bone and Joint Surgery (Br) 94-B : 218.
- Wu, J. J., Augustine, A., Holland, J. P. & Deehan, D. (2012). Oxidation and fusion defects synergistically accelerate polyethylene failure in knee replacement. The Knee 19(2): 124-129.
- Wu JJ, Wang Q, Simpson D & Collins S (2011). Biotribological and Structural Analyses of Large Diameter Ceramic on Carbon Fibre Reinforced PEEK Hip Joints with Different Inclination. Proceedings of International Conference on Biotribology
- Wang Q, Wu J J, Simpson D, Collins S, Briscoe B & Jarman-Smith M (2011). Biotribology of 40mm Diameter MOTIS PEEK on Ceramic Hip Joints: A Detailed Simulator Study with Different Inclination Angles. Proceedings of the 24th Annual Congress of ISTA
- Giddings D, Wu JJ & Khan I (2011). Excellent Performance of Novel Hip Bearings with Third Generation Superlattice Coating. Proc IMeChE Engineers and Surgeons: Joined at the hip III
- Field, R & Wu, JJ (2011). Modelling of permeability loss in membrane filtration: Re-examination of fundamental fouling equations and their link to critical flux. Desalination 283: 68-74.
- Lovelady, E., Kimmins, S., Wu, J. J. & Cameron, N. (2011). Preparation of emulsion-templated porous polymers using thiol–ene and thiol–yne chemistry. Polymer Chemistry 2(3): 559-562.
- Giddings D, Wu JJ, Mak SY & Khan I (2011). Prosim Simulator Wear Study of 60mm Diameter Zirconia Toughened Alumina Composite Hip Bearings: The Effect of High Cup Inclination Angle and Microseparation. Proceedings of International Conference on Biotribology
- Williams, S. R., Wu, J. J., Unsworth, A. & Khan, I. (2011). Wear and surface analysis of 38 mm ceramic-on-metal total hip replacements under standard and severe wear testing conditions. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 225(8): 783-796.
- Williams S, Wu J J, Unsworth A & Khan I (2010). Wear, Friction and Surface Analysis of 38mm ceramic-on-metal total joint hip replacements. Journal of Bone and Joint Surgery (Br) 92-B: 101-102.
- Hutchings, L.R., Dodds, J.M., Rees, D., Kimani, S.M., Wu, J.J. & Smith, E. (2009). HyperMacs to HyperBlocks: A Novel Class of Branched Thermoplastic Elastomer. Macromolecules 42(22): 8675-8687.
- Wang Q Q & Wu J J (2009). Numerical Prediction on Mechanical Contacts Vanguard Knee Joint replacements Tested in the Displacement-Controlled Prosim Simulator. Proceedings of IMeChE Knee Arthroplasty: From Early Intervention to Revision 289-292.
- Reay E, Wu J J, Holland J & Deehan D (2009). Premature failure of Kinemax Plus total knee replacements. Journal of Bone and Joint Surgery - British Volume 91-B(8): 604-611.
- Williams SR, Wu JJ, Unsworth A & Khan I (2009). Tribological and Surface Analysis of 38mm alumina-as cast CoCrMo Total Hip Arthroplasties. Proc. IMechE Part H: Journal of Engineering in Medicine 223: 941-954.
- Williams S R, Wu J J, Unsworth A & Khan I (2009). Tribological and surface analysis of 38mm alumina-as-cast Co-Cr-Mo total hip Arthroplasties. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 223(8): 941-954.
- Tholozan F Goldberg M Przyborski S, Wu J J & Quinlan R (2008). Bovine Lens Capsule-derived 3D matrices: Significance to the Maintenance of Lens Epthelial Cell Phenotype in in vitro Culture Models. ARVO 2008 Annual Meeting Eyes on Innovation
- Datta, H.K., Wu, J.J., Tuck, Stephen & Walker, J. (2008). Emerging Evidence of Osteocytes as Mechanosensors and Regulators of Mineralisation. Euopean Musculoskeletal Review 3(2): 48-52.
- Williams S, Wu J J, Unsworth A & Khan I (2008). Wear friction and surface analysis of 38mm ceramic-on-metal total hip replacements. Proc 21st Annual Congress of the International Society for Technology in Arthroplasty 91.
- Wu, J.J. (2006). Quantitative constitutive behaviour and viscoelastic properties of fresh flexor tendons. The International Journal of Artificial Organs 29(9): 852-857.
- Buckley, C.P., Wu, J.J. & Haughie, D.W. (2006). The integrity of welded interfaces in ultra high molecular weight polyethylene: Part 1 Model. Biomaterials 27(17): 3178-3186.
- Haughie, D.W., Buckley, C.P. & Wu, J.J. (2006). The integrity of welded interfaces in ultra-high molecular weight polyethylene: Part 2 - Interface Toughness. Biomaterials 27(21): 3875-3881.
- Wu, J. J. & Buckley, C. P. (2004). Plastic deformation of glassy polystyrene a unified model of yield and the role of chain length. Journal of polymer science part B polymer physics 42(11): 2027-2040.
- Wu, J. J., Buckley, C. P. & O'Connor, J. J. (2002). Mechanical integrity of compression-moulded ultra-high molecular weight polyethylene effects of varying process conditions. Biomaterials 23(17): 3773-3783.
- Wu, J. J., Buckley, C. P. & O'Connor, J. J. (2002). Processing of ultra-high molecular weight polyethylene modelling the decay of fusion defects. Chemical engineering research and design official journal of the European federation of chemical engineering part A 80(A5): 423-431.
- Wu, J. J., Buckley, C. P. & O'Connor, J. J. (2001). The origin of fusion defects in ultra-high molecular weight polyethylene for joint replacement prostheses. Journal of materials science letters 20(5): 473-475.
- Quinlan, R.A., Wu, J.J., Wu, W., Saunter, C. & Girkin, J. (2015), A mathematical model of the eye lens epithelium of mammals that predicts cell density profiles in the ageing lens, ARVO 2015 Annual Meeting. Denver, Colorado, ARVO.
- Lal, S. & Wu, J. J. (2015), Effect of Knee, Ankle and Hip Joint Replacements on Vitamin E Infused Highly Crosslinked UHMWPE Wear Particles Size, Shape and Morphologies Using a New Modified Base Digestion Method, 7th International UHMWPE Meeting. Philadelphia, PA.
- Wu, J.J., Andrews, R., Quinlan, R. & Tholozan, F. (2014), Do structural alterations mediated by enzymatic activities influence the mechanical properties of capsular biomembranes?, 10th International Congress on Membranes and Membrane Processes.
- Wu, Jun Jie, Stanley, Martin & Khan, Imran (2009), Biotribological and Structural Characterisations of Total Knee Replacements: A Prosim Knee Simulator Study, Knee Arthroplasty 2009: From Early Intervention to Intervention. London, Institution of Mechanical Engineers, 89-94.
- Buckley, C.P. & Wu, J.J. (2003), Anisotropic plastic deformation of glassy polymers with process-induced molecular orientation, 19th Annual Meeting of the Polymer Processing Society. Melbourne, Australia.
- Wu, J.J. & Buckley, C.P. (2003), The role of molecular parameters in the plastic deformation of glassy polystyrene, 12th International Conference on Deformation Yield and Fracture of Polymers. Cambridge, UK, The Institute of Materials, London.
- Wu, J.J. & Buckley, C.P. (2002), Deformation modelling of glassy polymers incorporating structural change, Annual Technical Conference of the Society of Plastics Engineers. San Fransisco, USA.
- Wu, J.J., Buckley, C.P. & O'Connor, J.J. (2000), Interparticle Bonding in Ultra-high Molecular Weight Polyethylene and its Control via Process Parameters, in Duckett, A.R. eds, 11th International Conference on Deformation Yield and Fracture of Polymers. Cambridge, UK, IOM Communications, London.
- O’Connor, J.J., Wu, J.J. & Buckley, C.P. (2006). Method of Compression Moulding of Polymer Powder. European Patent: Patent No. EP1165300. Application filed: 30 November 1999. Granted: 30 November 1999
- Wu, J.J., Buckley, C.P. & O'Connor, J.J. (2004). Integrity of compression moulded UHMWPE components. US Patent: Patent No. US 6677415. Application filed: 30 November 1999. Granted: 30 November 1999
- O’Connor, J.J., Wu, J.J. & Buckley, CP. (2004). Method of Compression Moulding of Polymer Powder and Product Produced. US Patent: Patent No. US 6677415. Application filed: 30 November 1999. Granted: 30 November 1999
- Wu JJ, Buckley CP & O'Connor JJ (1999). Compression Moulding. UK9907843. Application filed: 30 November 1999. Granted: 30 November 1999