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Email and Telephone Directory

Staff Profile

Dr Andrew Chaytor, BSc. (Hons), PhD

Telephone: +44 (0) 191 33 40339
Fax: +44 (0) 191 33 40321
Room number: C141, Holliday Building, Queen's Campus, Stockton
Lecturer in Pharmacology in the Centre for Medical Education Research
Lecturer in Pharmacology (Foundation Strand Leader) in Phase 1 Medicine

Contact Dr Andrew Chaytor

Biography

Andrew is Admissions Lead for Undergraduate Medicine, Lecturer in Pharmacology and Strand Leader for Foundation Case in the School of Medicine, Pharmacy & Health.

He gained his PhD in Cardiovascular Physiology and Pharmacology at the University of Wales College of Medicine, Cardiff investigating mechanisms of cellular communication in arteries and the chaos and nonlinear dynamics of blood vessel tone.

Previously Andrew worked as a British Heart Foundation Research Fellow and Lecturer at the Wales Heart Research Institute, Wales College of Medicine, Cardiff and as a Senior Lecturer in Physiology at the School of Pharmacy, University of Sunderland. His research is in Medical Education focussing on Admissions and Recruitment to Medical Schools, Professionalism and the Conscientiousness Index, Simulation and the teaching of Substance Misuse in the undergraduate medical curriculum.

Interests

Andrew is a member of Hunwick Harriers Running Club and has taken part in the London Marathon, Great North Run, Redcar half marathon, Stockton River Rat Race, many 10K races.

Research Groups

Medicine, Pharmacy and Health, School of

Research Interests

  • Admissions and Recruitment to Medical Schools
  • Simulation in UG Medicine
  • Use of a Conscientiousness Index as a measure of Professionalism
  • Substance misuse in the undergraduate medical curriculum
  • Mechanisms of arterial vasodilation
  • Role of gap junctions in the cardiovascular system

Teaching Areas

  • Cell Biology and Genetics
  • Clinical Skills
  • Pharmacology and Therapeutics (Phase I Medicine)
  • Physiology

Publications

Books: sections

  • Chaytor AT (2013). The Heart, Circulatory System, Major Arteries and Veins, Lymphatic System, Autonomic Nervous System. In 30 Second Anatomy. Finn GM Ivy Press.
  • Griffith, TM, Chaytor, AT & Edwards, DH (2003). Permissive role of cAMP in the mediation of electrotonic endothelium- and gap junction-dependent relaxations. In EDHF 2002. Vanhoutte, PM Taylor and Francis, London and New York.
  • Chaytor, AT, Hutcheson, IR, Marsh, WL & Griffith, TM (2001). Comparison of alpha and beta isoforms of glycyrrhetinic acid and carbenoxolone as inhibitors of EDHF-type relaxation. In EDHF 2000. Vanhoutte, PM Taylor and Francis, London and New York. 102-112.
  • Griffith, TM, Chaytor, AT, Berman, R & Edwards, DH (2001). Heterogeneity of EDHF-type relaxations analysed with peptides homologous to the extracellular loops of connexins 37, 40 and 43. In EDHF 2000. Vanhoutte, PM Taylor and Francis, London and New York. 62-75.
  • Griffith, TM, Chaytor, AT, Evans, W & Edwards, DH (1998). K+channels and integrated vascular control. In Microcirculation. Carpenter, PH, Vicaut, E & Guilmot, J-L Monduzzi Editore, Bologna, Italy.

Journal papers: academic

  • Carroll, J, Goodair, C, Chaytor, A, Notley, C, Ghodse, H & Kopelman, P (2014). Substance misuse teaching in undergraduate medical education. BMC Medical Education 14(1): 34.
  • Notley C, Goodair C, Chaytor A, Carroll J, Ghodse H & Kopelman P (2013). Report of the Substance Misuse in the Undergraduate Medical Curriculum Project in England. Drugs: Education, Prevention & Policy (May 16): 1-4.
  • Chaytor, AT, Armstrong, A, Spence J, & McLachlan JC (2012). Do students learn to be more conscientious at medical school? BMC Medical Education 12: 54.
  • Chaytor, AT (2009). Control of Cardiac Function: An Overview. Anaesthesia & Intensive Care Medicine 10(8): 370-72.
  • Chaytor, AT, Gray, C, Arrowsmith, C & Tan, I (2008). Effects of ascorbic acid on phenylephrine-evoked constriction and relaxation responses to acetylcholine in aorta from aged rats. Basic & Clinical Pharmacology & Toxicology 102: 26.
  • Edwards DH, Chaytor AT, Bakker LM & Griffith TM. (2007). Modulation of gap-junction-dependent arterial relaxation by ascorbic acid. Journal of Vascular Research 44(5): 410-422.
  • Griffith TM, Chaytor AT, Bakker LM & Edwards DH. (2005). 5-Methyltetrahydrofolate and tetrahydrobiopterin can modulate electrotonically mediated endothelium-dependent vascular relaxation. Proc Natl Acad Sci U S A 102(19): 7008-7013.
  • Edwards, DH, Chaytor, AT, Bakker, LM & Griffith, TM (2005). Antioxidant activity of 5-MTHF and BH4 can preserve EDHF-type responses by modulating electrotonic signalling. Journal of Vascular Research 42: 27.
  • Chaytor AT, Bakker LM, Edwards DH & Griffith TM. (2005). Connexin-mimetic peptides dissociate electrotonic EDHF-type signalling via myoendothelial and smooth muscle gap junctions in the iliac artery. Br J Pharmacol 144(1): 108-114.
  • Gavazza F, Daverio F, Chaytor AT, Griffith TM & McGuigan C. (2005). Phosphoramidate derivatives of 2',5'-dideoxyadenosine as potential inhibitors of the EDHF phenomenon. Nucleosides Nucleotides Nucleic Acids 24(5-7): 553-555.
  • Griffith TM, Chaytor AT, Edwards DH, Daverio F & McGuigan C. (2004). Enhanced inhibition of the EDHF phenomenon by a phenyl methoxyalaninyl phosphoramidate derivative of dideoxyadenosine. Br J Pharmacol 142(1): 27-30.
  • Griffith TM, Chaytor AT & Edwards DH. (2004). The obligatory link: role of gap junctional communication in endothelium-dependent smooth muscle hyperpolarization. Pharmacol Res 49(6): 551-564.
  • Ujiie H, Chaytor AT, Bakker LM & Griffith TM. (2003). Essential role of Gap junctions in NO- and prostanoid-independent relaxations evoked by acetylcholine in intracerebral arteries. Stroke 34(2): 544-550.
  • Griffith TM, Chaytor AT, Taylor HJ, Giddings BD & Edwards DH. (2002). cAMP facilitates EDHF-type relaxations in conduit arteries by enhancing electrotonic conduction via gap junctions. Proc Natl Acad Sci U S A 99(9): 6392-7.
  • Chaytor AT, Taylor HJ & Griffith TM. (2002). Gap junction-dependent and -independent EDHF-type relaxations may involve smooth muscle cAMP accumulation. Am J Physiol Heart Circ Physiol 282(4): H1548-5.
  • Taylor HJ, Chaytor AT, Edwards DH & Griffith TM. (2001). Gap junction-dependent increases in smooth muscle cAMP underpin the EDHF phenomenon in arteries. Biochem Biophys Res Commun 283(3): 583-9.
  • Chaytor AT, Martin PE, Edwards DH & Griffith TM. (2001). Gap junctional communication underpins EDHF-type relaxations evoked by ACh in the hepatic artery. Am J Physiol Heart Circ Physiol 280(6): H2441-50.
  • Chaytor AT, Marsh WL, Hutcheson IR & Griffith TM. (2000). Comparison of glycyrrhetinic acid isoforms and carbenoxolone as inhibitors of EDHF-type relaxations mediated via gap junctions. Endothelium 7(4): 265-78.
  • Hutcheson IR, Chaytor AT, Evans WH & Griffith TM (1999). Nitric oxide-independent relaxations to acetylcholine and A23187 involve different routes of heterocellular communication. Role of Gap junctions and phospholipase A2. Circ Res 84(1): 53-63.
  • Dora KA, Martin PE, Chaytor AT, Evans WH, Garland CJ & Griffith TM. (1999). Role of heterocellular Gap junctional communication in endothelium-dependent smooth muscle hyperpolarization: inhibition by a connexin-mimetic peptide. Biochem Biophys Res Commun 254(1): 27-31.
  • Chaytor AT, Martin PE, Evans WH, Randall MD & Griffith TM. (1999). The endothelial component of cannabinoid-induced relaxation in mesenteric artery depends on gap junctional communication. J Physiol 520(2): 539-50.
  • Chaytor AT, Evans WH & Griffith TM. (1998). Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J Physiol 508(2): 561-73.
  • Chaytor AT, Evans WH & Griffith TM. (1997). Peptides homologous to extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in arteries. J Physiol 503(1): 99-110.

Books: online

  • Chaytor, AT (2008). Benzodiazepines: Alprazolam, Chlordiazepoxide, Clonazepam, Diazepam, Flurazepam, Triazolam. Elsevier Inc.

Conference papers

  • Chaytor, AT, Finn, G & Sawdon, M (2013), Components of the Conscientiousness Index and Peer Estimates of Professionalism, AMEE 2013. Prague, Czech Republic.
  • Chaytor, AT, Goodair, C, Notley, C & Ghodse, H (2012), An Evaluation of the Teaching of Substance misuse in the undergraduate medical curriculum, ASME 2012. Brighton, UK.
  • Hyde-Wesson C, Chaytor AT & Sawdon M (2012), Conscientious behaviour is a predictor of academic outcome in Foundation Programme students, Society for Research in Higher Education. Celtic Manor, Newport, UK.
  • Sawdon, M, Finn, G, Chaytor, AT & McLachlan, JC (2012), Diligence is the mother of good fortune” measuring conscientiousness in health care settings, AMEE Ottawa Conference on the Assessment of Competence in Medicine and the Healthcare Professions. Kuala Lumpur, Malaysia.
  • Chaytor AT (2012), Is Conscientious Behaviour in Medical Students Modified by Teaching and Clinical Exposure, ASME 2012. Brighton, UK.
  • Chaytor, AT (2011), Teaching of substance misuse in the undergraduate medical curriculum, AMEE 2011. Vienna, Austria.
  • Curtis, F, Sawdon, M & Chaytor, AT (2010), eFeedback: enhancing student learning, a multifaceted approach, eAssessment Scotland 2010. Dundee, UK.
  • Chaytor, AT (2008), Effects of ascorbic acid on vascular tone in aorta from aged subjects, EDHF 2008 International Symposium. Tampere, Finland.
  • Chaytor, AT (2006), Endothelium dependent mechanisms of vasodilatation, British Hypertension and Vascular Research Group. Turnberry, UK.
  • Edwards, DH, Chaytor, AT, Bakker, LM & Griffith, TM (2005), Antioxidant activity of 5-MTHF and BH4 can preserve EDHF-type responses by modulating electrotonic signalling, 9th International Symposium on Mechanisms of Vasodilatation and Endothelium-Derived Hyperpolarizing Factors (EDHF). Antwerp, BELGIUM.
  • Chaytor, AT (2005), NO-independent mechanisms of vasodilatation: the role of gap junctions and hydrogen peroxide, British Hypertension and Vascular Research Group. Gleneagles, UK.
  • Chaytor, AT & Griffith, TM (2004), Gap Junctional Communication in Arteries, British Pharmacological Society. Bath, UK.
  • Chaytor, AT & Griffith, TM (2003), Role of Gap Junctions in Endothelium-dependent Relaxation, 3rd Federation of European Physiological Societies Congress. Nice, France.
  • Chaytor, AT & Griffith, TM (2002), Role of Gap Junctions in EDHF at the 4th Symposium on EDHF (June 5th-8th, 2002), L'Abbaye de Cernay, Paris, France, 4th International Symposium on EDHF. L'Abbaye de Cernay, Paris, France.
  • Chaytor, AT, Edwards, DH & Griffith, TM (2002), Role of Gap Junctions in the Arterial Wall, Annual Meeting of the Association of Physicians of Great Britain and Ireland. St Davids Hall, Cardiff, UK.
  • Chaytor, AT (2002), Role of gap junctions in the arterial wall, 2nd UK Gap Junction Conference. UCL, London.
  • Chaytor, AT (2001), Connexin proteins in the arterial wall, Pharmacology Vancouver – Joint meeting of the Australian, British, Canadian and Western Pharmacological Societies. University of British Columbia, Vancouver, BC, Canada..
  • Chaytor, AT & Griffith, TM (2001), Role of connexin proteins in EDHF-type relaxation responses, 8th International Symposium on Mechanisms of Vasodilatation. Boston, USA..
  • Chaytor, AT (2001), Role of connexin proteins in the arterial wall, 1st UK Gap Junction Conference. Royal London Hospital, London.
  • Chaytor, AT (2000), Connexin-mimetic peptides block EDHF-type relxations in arteries, British Pharmacological Society. Cardiff University, Cardiff..
  • Chaytor, AT (2000), EDHF-type responses in arterials are mediated by gap junctions, 3rd International Symposium on EDHF. L'Abbaye de Cernay, Paris, France.
  • Griffith, TM, Chaytor, AT & Edwards, DH (2000), Non-linear dynamics and the control of vascular tone, 1st European Study Group on Cardiovascular Oscillations. Miskin Manor, Cardiff.

Reports: official

  • Notley, C, Chaytor, A, Terry, D, Carroll, J, Sandor, A, Goodair, C & Ghodse, H (2012). Substance Misuse in the Undergraduate Medical Curriculum Project Report. International Centre for Drugs Policy (ICDP), St George's University of London.

Media Contacts

Available for media contact about:

  • Health & Welfare: Effects of medicines and drugs on the human body

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