Publication details for Dr Robert PalButler, S.J., Delbianco, M., Lamarque, L., McMahon, B.K., Neil, E.R., Pal, R., Parker, D., Walton, J.W. & Zwier, J. (2015). EuroTracker® dyes design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging. Dalton Transactions 44(11): 4791-4803.
- Publication type: Journal Article
- ISSN/ISBN: 1477-9226, 1477-9234
- DOI: 10.1039/C4DT02785J
- Further publication details on publisher web site
- Durham Research Online (DRO) - may include full text
Author(s) from Durham
The development of the brightest luminescent europium(III) complexes is traced, including analysis of the C3-symmetric core complex based on a functionalized triazacyclononane and identification of the most suitable strongly absorbing chromophore. Strategies for the synthesis of the complexes, including enantiopure analogues, are outlined and opportunities for applications in time-resolved microscopy and spectral imaging emphasised. Practicable examples are introduced, including selective organelle staining for cellular optical imaging at 65 nm resolution and the development of new bioassays using time-resolved FRET methods.