Publication details for Prof. Ivana EvansHarriss, Bethany I., Vella-Zarb, Liana, Wilson, Claire & Radosavljevic Evans, Ivana (2014). Furosemide Cocrystals: Structures, Hydrogen Bonding, and Implications for Properties. Crystal Growth and Design 14(2): 783-791.
- Publication type: Journal Article
- ISSN/ISBN: 1528-7483, 1528-7505
- DOI: 10.1021/cg401662d
- Further publication details on publisher web site
- Durham Research Online (DRO) - may include full text
Author(s) from Durham
Four new crystal structures of pharmaceutical molecule furosemide with GRAS coformers are reported and correlated with the known pharmacologically relevant properties of these materials. Furosemide carboxylic acid oxygen donor−coformer aromatic nitrogen acceptor is the dominant synthon, leading to the key intermolecular interactions in the cocrystals studied.