Cookies

We use cookies to ensure that we give you the best experience on our website. You can change your cookie settings at any time. Otherwise, we'll assume you're OK to continue.

Durham University

Department of Biosciences

Profile

Publication details for Professor Martin Cann

Bretonnière, Y., Cann, M.J., Parker, D. & Slater, R. (2002). Ratiometric probes for hydrogencarbonate analysis in intracellular or extracellular environments using europium luminescence. Chemical Communications 2002(17): 1930-1931.

Author(s) from Durham

Abstract

A series of six, cationic, zwitterionic and anionic Eu complexes has been examined for the analysis of hydrogencarbonate concentration in the intracellular and extracellular ranges; an anionic complex incorporating three glutarate residues and a sensitising acridone chromophore (lambda exc = 410 nm) exhibits a 69% change in the intensity ratio of the 618/588 nm Eu emission bands between 5 and 15 mM HCO3- in a cell lysate medium.