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Department of Physics

Staff profile

Publication details for Dr Elizabeth Bromley

Channon, K, Bromley, EHC & Woolfson, DN (2008). Synthetic biology through biomolecular design and engineering. Current Opinion In Structural Biology 18(4): 491-498.
  • Publication type: Journal papers: academic
  • ISSN/ISBN: 0959-440X

Author(s) from Durham

Abstract

Synthetic biology is a rapidly growing field that has emerged in a
global, multidisciplinary effort among biologists, chemists, engineers,
physicists, and mathematicians. Broadly, the field has two
complementary goals: To improve understanding of biological systems
through mimicry and to produce bioorthogonal systems with new
functions. Here we review the area specifically with reference to the
concept of synthetic biology space, that is, a hierarchy of components
for, and approaches to generating new synthetic and functional systems
to test, advance, and apply our understanding of biological systems. In
keeping with this issue of Current Opinion in Structural Biology, we
focus largely on the design and engineering of biomolecule-based
components and systems.