(A full list of publications since 1979 can be found here
A bright and responsive europium probe for determination of pH change within the endoplasmit reticulum of living cells, Chem. Commun, 2013, in Press (with B. K. McMahon and R. Pal) .
Conformational analysis and synthetic approaches to polydentate perhydro-diazepine ligands for the complexation of gallium(III), Org. Biomol. Chem, 2013, 11, 2827-2838 (with B. P. Waldron).
Very bright europium complexes that stain cellular mitochondria, Chem. Commun.,2013, 49, 1600-1602 (with J. W. Walton, A. Bourdolle, S. J. Butler, M. Soulie, M. Delbianco, B. K. McMahon, R. Pal, H. Puschmann, J. M. Zwier, L. Lamarque, O. Maury and C. Andraud).
Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68, Chem. Commun., 2013, 49, 579-581 (with B. P. Waldron, C. Burchardt, D. S. Yufit, M. Zimny and F. Roesh).
Experimental Measurement and Theoretical Assessment of Fast Lanthanide Electronic Relaxation in Solution with Four Series of Isostructural Complexes, J. Phys. Chem. A, 2013, 117, 905-917 (with A. M. Funk, P. H. Fries, P. Harvey and A. M. Kenwright).
Anion binding in water at lanthanide centres: from structure and selectivity to signalling and sensing, Chem. Soc. Rev., 2013, 42, 1652-1666 (with S. J. Butler).
Lanthanide complexes as chiral probes exploiting circularly polarized luminescence, Chem. Soc. Rev., 2012, 7673-7686 (with R.Carr and N. H. Evans).
Live cell imaging of lysosomal pH changes with pH responsive ratiometric lanthanide probes, Chem. Commun., 2012, 48, 8520-8522 (with D. G. Smith, B. K. McMahon and R. Pal).
Measuring equilibrium bicarbonate concentrations directly in cellular mitochondria and in human serum using europium/terbium emission intensity ratios, Chem. Eur. J., 2012, 18, 11604-11613 (with D. G. Smith and R. Pal).
Boosting 19F MRI-SNR-efficient detection of paramagnetic contrast agents using ultra-fast sequences, Magn. Reson. Med., 2012, 69, 1056-1062 (with F. Schmid, C. Holtke and C. Faber).
Paramagnetic 19F chemical shift probes probes that respond selectively to calcium or citrate levels and signal ester hydrolysis, Chem. Eur. J., 2012, 18, 8748-8757 (with P. Harvey, A. Mishra, K. H. Chalmers and E. De Luca).
Isostructural series of chiral nine-coordinate lanthanide complexes based on triazacyclononane, Inorg. Chem., 2012, 51, 8042-8056 (with J. W. Walton, R. Carr, N. H. Evans, A. M. Funk, A. M. Kenwright, D. S. Yufit, M. Botta, S. De Pinto, and K-L. Wong).
A chiral probe for alpha-acid glycoprotein and alpha-1-antitrypsin based on europium luminescence, Dalton Trans., 2012, 41, 13154-13158 (with R. Carr, L. Di Bari, S. Lo Piano, R. D. Peacock and J. M. Sanderson).
Lanthanide complexes as paramagnetic probes for 19F magnetic resonance, Eur. J. Inorg. Chem., 2012, 2015-2022 (with P. Harvey and I. Kuprov).
Responsive imaging probes for metabotropic glutamate receptors, Chem. Sci., 2012, 3, 131-135 (with A. Mishra, J. Engelmann and S. Gottschalk).
Structure, resolution and chiroptical analysis of stable lanthanide complexes of a pyridylphenylphosphinate triazacyclononane ligand, Chem. Commun., 2011, 47, 12289-12291 (with J. W. Walton, L. Di Bari, G. Pescitelli, H. Puschmann and D.S. Yufit).
Rapid and accurate analysis of citrate in low-volume seminal fluid samples using a time-gated and ratiometric measurement of europium luminescence, J. Pharmaceut. Biomed. Anal., 2011, 56, 352– 358 (with R. Pal and A. Beeby).
Enantioselective binding of a lanthanide(III) complex to human serum albumin studied by 1H NMR STD techniques, Org. Biomol. Chem., 2011, 9, 5047-5050 (with D. M. Dias, J. M. C. Teixeira, I. Kuprov, E. J. New, and C. F. G. C. Geraldes).
Evidence for the optical signalling of changes in bicarbonate
concentration within the mitochondrial region of living cells, Chem. Commun., 2011, 47, 7347-7349
(with D. G. Smith, Ga-Lai Law, B. S. Murray, R. Pal and Ka-Leung Wong).
19F-Lanthanide complexes With increased sensitivity for
19F-MRI: Optimization of the MR aquisition, Magn. Reson. Med., 2011, 66, 931-936 (with K. H. Chalmers, A. M. Kenwright and A. M. Blamire).
Critical design factors for optical imaging with metal coordination complexes, Aust. J. Chem., 2011, 64, 239-243.
Critical in vitro evaluation of responsive MRI contrast agents for
calcium and zinc, Chem. Eur. J. 2011, 17, 1529 – 1537 (with A. Mishra and N. K. Logothetis).
Strategies to enhance signal intensity with paramagnetic fluorine-labelled lanthanide complexes as probes for 19F magnetic resonance, Dalton Trans., 2011, 40, 904-913 (with K. H. Chalmers and M. Botta).
Comparative study of the luminescence properties and relative stability of a series of europium(III) complexes bearing one to four coordinated azaxanthone group, Eur. J. Inorg. Chem., 2010, 25, 3961-3966 (with J. W. Walton and L. L. Lamarque).
Synthesis and comparative anion binding profiles of two di-aqua Eu(III) complexes, Dalton Trans., 2010, 39, 9897-9903 (with D. Imperio, G. B. Giovenzana, Ga-lai Law, and J. W. Walton).
Definition of the uptake mechanism and sub-cellular localisation profile of emissive lanthanide complexes as cellular optical probes, Chemical Science, 2010, 1, 111-118 (with E. J. New and A. Congreve).
Synthesis, Chirality and Complexation Phenomena of Two Diastereoisomeric Dinuclear Lanthanide(III) Complexes
, Eur. J. Inorg. Chem., 2010, 18, 2663-2672 (with B. S. Murray, C. M. G. dos Santos and R. D. Peacock).
Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(III) complex, Chem. Commun., 2010, 46, 2391-2393 (with Ga-Lai Law, C. Man and J. W. Walton).
Design Principles and Theory of Paramagnetic Fluorine-Labelled Lanthanide Complexes as Probes for 19F Magnetic Resonance: A Proof-of-Concept Study, Chem. Eur. J, 2010, 16, 134-148 (with K. H. Chalmers, E. De Luca, N. H. M. Hogg, A. M. Kenwright, I. Kuprov, M. Botta, I. Wilson and A. Blamire).
Development of responsive lanthanide probes for cellular applications, Cur. Opin. Chem. Bio., 2010, 14, 238-246 (with E. J. New, D. G. Smith and J. W. Walton).
Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing, Chem. Commun., 2009, 7321-7323 (with Ga-Lai Law, Robert Pal, Lars O. Palsson and Ka-Leung Wong).
The mechanism of quenching of the lanthanide excited state for optical probes using sensitised emission, Dalton Trans., 2009, 8481-8484 (with Ga-Lai Law, Siobhan L. Richardson and Ka-Leung Wong).
The mechanism of cell uptake for luminescent lanthanide optical probes: the role of macropinocytosis and the effect of enhanced membrane permeability on compartmentalisation, Org. Biomol. Chem., 2009, 7, 851-855 (with Elizabeth J. New).
Cell-Penetrating Metal Complex Optical Probes: Targeted and Responsive Systems Based on Lanthanide Luminescence, Acc. Chem. Res., 2009, 42, 925-937 (with Craig P. Montgomery, Benjamin S. Murray, Elizabeth J. New and Robert Pal).
Variation of water exchange dynamics with ligand structure and stereochemistry in lanthanide complexes based on 1,4-diazepine derivatives, Org. Biomol. Chem., 2009 (with Elisa M. Elemento, Silvio Aime, Eliana Gianolio and Luciano Lattuada).
A europium luminescence assay of lactate and citrate in biological fluids, Org. Biomol. Chem., 2009, 7, 1525-1528, (with Robert Pal and Leslie C. Costello).
Electron-capture dissociation and collision-induced dissociation of lanthanide metal-ligand complexes and lanthanide metal-ligand complexes bound to phosphopeptides, European Journal of Mass Spectrometry., 2009, 2, 145-155 (with Jackie A. Mosely and Benjamin S. Murray).
Variation of water exchange dynamics with ligand structure and stereochemistry in lanthanide complexes based on 1,4-diazepine derivatives, Org. Biomol. Chem., 2009, 7, 1120-1131 (with Elisa M. Elemento, Silvio Aime, Eliana Gianolio and Luciano Lattuada).
Comparative study of the constitution and chiroptical properties of emissive terbium and europium complexes with a common tetraazatriphenylene sensitiser; the nature of the sensitiser determines quenching sensitivity and cellular uptake, Dalton Trans., 2009, 672-679 (with Elizabeth J. New and Robert D. Peacock).
Enantioselective regulation of a metal complex in reversible binding to serum albumin: dynamic helicity inversion signalled by circularly polarised luminescence, Chem. Commun., 2008, 4261-4263 (with Craig P. Montgomery, Elizabeth J. New and Robert D. Peacock).
The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use, Org. Biomol. Chem., 2008, 6, 2256-2258 (with Filip Kielar, Ga-Lai Law and Elizabeth J. New).
Two-photon microscopy study of the intracellular compartmentalisation of emissive terbium complexes and their oligo-arginine and oligo-guanidinium conjugates, Chem. Commun., 2008, 2435-2437 (with Filip Kielar, Aileen Congreve, Ga-lai Law, Elizabeth J. New, Ka-Leung Wong, Pilar Castreno and Javier de Mendoza).
19F NMR based pH probes: lanthanide(III) complexes with pH-sensitive chemical shifts, Chem. Commun., 2008, 2514-2516 (with Alan M. Kenwright, Ilya Kuprov, Elena De Luca, Shashi U. Pandya, P. Kanthi Senanayake and David G. Smith).
Critical evaluation of five emissive europium(III) complexes as optical probes: correlation of cytotoxicity, anion and protein affinity with complex structure, stability and intracellular localisation profile, Org. Biomol. Chem., 2008, 6, 2085-2094 (with Benjamin S. Murray, Elizabeth J. New and Robert Pal).
A ratiometric optical imaging probe for intracellular pH based on modulation of europium emission, Org. Biomol. Chem., 2008, 6, 1020-1033 (with Robert Pal).
Enantioselective catalysis of the Henry reaction by a chiral macrocyclic ytterbium complex in aqueous media, Org. Biomol. Chem., 2007, 5, 3842-3846 (with Shashi U. Pandya and Rachel S. Dickins).
Two-photon absorption and photoluminescence of europium based emissive probes for bioactive systems
, Dalton Trans., 2007, 5726-5734 (with Lars-Olof Pålsson, Robert Pal, Benjamin S. Murray and Andrew Beeby).
Effective and efficient sensitisation of terbium luminescence at 355 nm with cell permeable pyrazoyl-1-azaxanthone macrocyclic complexes
, Chem. Comm., 2007, 3841-3842 (with Craig P. Montgomery, Laurent Lamarque). HTML of this article with enhanced links here
A mechanistic study of the dynamic quenching of the excited state of europium(III) and terbium(III) macrocyclic complexes by charge- or electron transfer
, Org. Biomol. Chem., 2007, 5, 2975-2982 (with Filip Kielar, Craig P. Montgomery, Elizabeth J. New, Robert A. Poole, Siobhan L. Richardson, Philip A. Stenson).
Responsive fluorinated lanthanide probes for 19F magnetic resonance spectroscopy, Chem. Commun., 2007, 2923-2925 (with Kanthi Senanyake, Alan Kenwright and Susanna van der Hoorn).
Identification of emissive lanthanide complexes suitable for cellular imaging that resist quenching by endogenous anti-oxidants, Org. Biomol. Chem., 2007, 5, 2055-2062 (with Robert Poole, Craig Montgomery, Elizabeth New, Aileen Congreve and Mauro Botta).
A single component ratiometric pH probe with long wavelength excitation of europium emission, Chem. Commun., 2007, 474-476 (with Robert Pal).
Synthesis and characterisation of dimeric eight-coordinate lanthanide(III) complexes of a macrocyclic tribenzylphosphinate ligand, Dalton Trans., 2006, 5423-5428 (with Kanthi Senanayake, Amber L. Thompson, Judith A. K. Howard, Mauro Botta).
A ratiometric and non-enzymatic luminescence assay for uric acid: differential quenching of lanthanide excited states by anti-oxidants, Chem. Commun., 2006, 4084-4086 (with Robert A. Poole, Filip Kielar, Siobhan L. Richardson, Philip A. Stenson).
On the role of the counter-ion in defining water structure and dynamics: order, structure and dynamics in hydrophilic and hydrophobic gadolinium salt complexes, Dalton Trans., 2006, 5605-5616 (with Amber L. Thompson, David A. Fulton, Judith A. K. Howard, Shashi U. Pandya, Horst Puschmann, Kanthi Senanayake, Philip A. Stenson, Alessandra Badari, Mauro Botta, Stefano Avedano and Silvio Aime).
A cationic lanthanide complex binds selectively to phosphorylated tyrosine sites, aiding NMR analysis of the phosphorylated insulin receptor peptide fragment, Org. Biomol. Chem, 2006, 4, 3166-3171 (with Paul Atkinson and Ben Murray).
Structural characterisation of a diprotonated ligand lanthanide complex—a key intermediate in lanthanide ion association and complex dissociation pathways, Dalton Trans., 2006, 3291-3293 (with Philip Stenson and Amber Thompson).
Engineering emissive lanthanide complexes for molecular imaging and sensing, Dalton Trans., 2006, 2757-2766 (with Shashi Pandya and Junhua Yu).
Azaxanthones and azathioxanthones are effective sensitisers for europium and terbium luminescence, Org. Biomol. Chem., 2006, 4, 1707-1722 (with Paul Atkinson, Karen Findlay, Filip Kielar, Robert Pal, Robert Poole, Horst Puschmann, Siobhan Richardson, Philip Stenson, Amber Thompson and Junhua Yu).
Glycoconjugates of gadolinium complexes for MRI applications, Chem. Commun., 2006, 1064-1066 (with David Fulton, Elisa Elemento, Silvio Aime, Linda Chaabane and Mauro Botta).
A Europium Complex That Selectively Stains Nucleoli of Cells, J. Am. Chem. Soc., 2006, 128(7), 2294-2299 (with Junhua Yu, Robert Pal, Robert Poole and Martin Cann).
Synthesis of a europium complex for anion-sensing involving regioelective substitution of cyclen, Eur. J. Org. Chem., 2005, 4249-4252 (with Junhua Yu).
A pH-insensitive ratiometric chemosensor for citrate using europium luminescence, Chem. Commun., 2005, 3141-3143 (with Junhua Yu).
Signalling reversible anion binding in aqueous media, chapter 8 in Contemporary Macrocyclic Chemistry: Current Trends and Future Perspectives ed. K. Gloe, Springer, New York, 2005, 121-137 (with R. S. Dickins).
Synthesis and characterisation of highly emissive and kinetically stable lanthanide complexes suitable for usage in cellulo, Org. Biomol. Chem., 2005, 3, 1013-1024 (with R. A. Poole, G. Bobba, J-C. Frias, and M.J. Cann).
NMR and luminescence binding studies of ytterbium, thulium and europium macrocyclic complexes with phosphorus(V) oxyanions, Helv. Chim. Acta, 2005, 88, 391-405 (with P. Atkinson, Y. Bretonniere and G. Muller).
Efficient relaxivity enhancement in dendritic gadolinium complexes; effective motional coupling in medium MW conjugates, Chem. Commun., 2005, 474-476 (with D. Fulton, M. O’Halloran, K. Senanayake, M. Botta and S. Aime).