Electrochemical sensors both disposable and on-line, are developed and characterised for application in 'harsh' samples such as plasma, whole blood and brackish media.
Image opposite: Chronoamperograms showing Ca2+ efflux at rapid cooling rate (~ dT/dt = 0.16 °C/s) from Arabidopsis roots
Projects in this category range from:
Development of multi-analyte sensing platforms for medical and environmental applications.
Integrating sensing and separation on a single probe to enable sensors to be used directly in 'real' media such as whole blood and brackish water, using functionalized porous materials or magnetic nanoparticles.
Chiral sensing at a liquid-liquid interface and biological chiral interactions.
Measurement of intracellular ions, ROS/RNS in plant and mammalian cells and thiol redox proteins.
Sensor platforms are fabricated in collaboration with Professor David Wood (Engineering and Computer Sciences). We collaborate with Professor Marc Knight and Dr Adam Benham (Biological Sciences) for biological applications. ROS/RNS monitoring techniques are developed in a Royal Society funded project with Prof Christian Amatore's group (ENS, Paris). A clinical sensor for monitoring anaesthetic drugs is being developed in collaboration with Freeman Hospital, Newcastle.
Contact: Dr Ritu Kataky
R. Daunton, A. Gallant, D. Wood and R. Kataky, "A thermally actuated microgripper as an electrochemical sensor with the ability to manipulate single cells."Chem. Commun., 2011, Advance Article DOI: 10.1039/C1CC11904D First published on the web 26 Apr 2011.
A. Delcourt Lancon, D. Wood, A. Gallant, R. Kataky, "Microelectrode Arrays for Electroanalytical Sensing: Electroplating improves response compared to e-Beam Metallisation." Electrochem Commun, 13 (2011), pp. 414-417.
F. A. Aguiar, R. Campos, C. Wang, R. Jitchati, A. S. Batsanov, M. R. Bryce and R. Kataky, "Voltage and structure dependent self assembly and electron-transfer properties of rigid rod molecular wires." PCCP., 2010,12(44),14804-14811.
R. Md Zawawi, R. Kataky, "Modification of the chiral selectivity of D-glucose oxidase and L-lactate oxidase in a collagen matrix" PCCP, 2010, 12, 9183-9187.