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Biophysical Sciences Institute

Technologies for Bioprocessing

Advanced protein characterisation, protein folding and post-translational modification largely supported by BBSRC.


Project Details

Industrial Biotechnologies, including bioprocessing, are well represented in the regional economy. The BSI supports postgraduate training and research in this area (to technology readiness level four). Programmes in advanced protein characterisation range from coarse-grain modelling of protein folding in the soft matter and biological physics research group and Mathematical Sciences, to the interrogation of protein structure by spectroscopic methods and x-ray crystallography in the Department of Chemistry, to molecular cell biology and in vivo protein imaging approaches within the School of Biological and Biomedical Sciences.

Multiple programmes are directed towards the optimisation of protein folding and post-translational modification which are often rate limiting steps in the production of biologics. For example, with support from the bioprocessing research industry club, Martin Schroeder is characterising the protein unfolding response in the endoplasmic reticulum.  We are also developing new technologies for animal cell and tissue culture.

Contact: Professor Nigel Robinson

Contact Details

Biophysical Sciences Institute
Durham University.
South Road,
Durham,
DH1 3LE
+44 (0) 191 334 2351

email: admin.bsi@durham.ac.uk