Academic Staff
Publication details for Dr Martin Cann
Y. Bretonniere, M.J. Cann, D. Parker & R. Slater (2002). Ratiometric probes for hydrogencarbonate analysis in intracellular or extracellular environments using europium luminescence. Chem Commun (Camb) (17): 1930-1.- Publication type: Journal papers: academic
Author(s) from Durham
Abstract
A series of six, cationic, zwitterionic and anionic Eu complexes has been examined for the analysis of hydrogencarbonate concentration in the intracellular and extracellular ranges; an anionic complex incorporating three glutarate residues and a sensitising acridone chromophore (lambda exc = 410 nm) exhibits a 69% change in the intensity ratio of the 618/588 nm Eu emission bands between 5 and 15 mM HCO3- in a cell lysate medium.